Breast cancer complexity: implications of intratumoral heterogeneity in clinical management
B Haynes, A Sarma, P Nangia-Makker… - Cancer and Metastasis …, 2017 - Springer
Generation of intratumoral phenotypic and genetic heterogeneity has been attributed to
clonal evolution and cancer stem cells that together give rise to a tumor with complex …
clonal evolution and cancer stem cells that together give rise to a tumor with complex …
Functionally active Fc mutant antibodies recognizing cancer antigens generated rapidly at high yields
KM Ilieva, J Fazekas-Singer, DY Achkova… - Frontiers in …, 2017 - frontiersin.org
Monoclonal antibodies find broad application as therapy for various types of cancer by
employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated …
employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated …
Establishment of EMab-134, a sensitive and specific anti-epidermal growth factor receptor monoclonal antibody for detecting squamous cell carcinoma cells of the oral …
S Itai, S Yamada, MK Kaneko, YW Chang… - Monoclonal …, 2017 - liebertpub.com
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, activates downstream
signaling cascades in many tumors. In this study, we established novel anti-EGFR …
signaling cascades in many tumors. In this study, we established novel anti-EGFR …