Protein–protein interactions: detection, reliability assessment and applications
Protein–protein interactions (PPIs) participate in all important biological processes in living
organisms, such as catalyzing metabolic reactions, DNA replication, DNA transcription …
organisms, such as catalyzing metabolic reactions, DNA replication, DNA transcription …
The fundamental advantages of temporal networks
Most networked systems of scientific interest are characterized by temporal links, meaning
the network's structure changes over time. Link temporality has been shown to hinder many …
the network's structure changes over time. Link temporality has been shown to hinder many …
Construction of refined protein interaction network for predicting essential proteins
Identification of essential proteins based on protein interaction network (PIN) is a very
important and hot topic in the post genome era. Up to now, a number of network-based …
important and hot topic in the post genome era. Up to now, a number of network-based …
[HTML][HTML] Computational methods using genome-wide association studies to predict radiotherapy complications and to identify correlative molecular processes
JH Oh, S Kerns, H Ostrer, SN Powell, B Rosenstein… - Scientific reports, 2017 - nature.com
The biological cause of clinically observed variability of normal tissue damage following
radiotherapy is poorly understood. We hypothesized that machine/statistical learning …
radiotherapy is poorly understood. We hypothesized that machine/statistical learning …
Identification of protein complexes by using a spatial and temporal active protein interaction network
The rapid development of proteomics and high-throughput technologies has produced a
large amount of Protein-Protein Interaction (PPI) data, which makes it possible for …
large amount of Protein-Protein Interaction (PPI) data, which makes it possible for …
[图书][B] Computational prediction of protein complexes from protein interaction networks
Complexes of physically interacting proteins constitute fundamental functional units that
drive almost all biological processes within cells. A faithful reconstruction of the entire set of …
drive almost all biological processes within cells. A faithful reconstruction of the entire set of …
[HTML][HTML] CPredictor3. 0: detecting protein complexes from PPI networks with expression data and functional annotations
Background Effectively predicting protein complexes not only helps to understand the
structures and functions of proteins and their complexes, but also is useful for diagnosing …
structures and functions of proteins and their complexes, but also is useful for diagnosing …
Predicting protein complexes in weighted dynamic PPI networks based on ICSC
Protein complexes play a critical role in understanding the biological processes and the
functions of cellular mechanisms. Most existing protein complex detection algorithms cannot …
functions of cellular mechanisms. Most existing protein complex detection algorithms cannot …
A multi-objective biclustering algorithm based on fuzzy mathematics
X Zhu, J Qiu, M Xie, J Wang - Neurocomputing, 2017 - Elsevier
Biclustering algorithm is to cluster in the horizontal and vertical directions simultaneously in
matrix. This algorithm identifies a set of sub-matrix by adopting a greedy iterative strategy …
matrix. This algorithm identifies a set of sub-matrix by adopting a greedy iterative strategy …
[HTML][HTML] Identifying protein complex by integrating characteristic of core-attachment into dynamic PPI network
X Shen, L Yi, X Jiang, T He, J Yang, W Xie, P Hu, X Hu - PloS one, 2017 - journals.plos.org
How to identify protein complex is an important and challenging task in proteomics. It would
make great contribution to our knowledge of molecular mechanism in cell life activities …
make great contribution to our knowledge of molecular mechanism in cell life activities …