Circadian rhythm disturbances are a common symptom among individuals with mood
disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior …

Over recent years, a deeper comprehension of the molecular mechanisms that control
biological clocks and circadian rhythms has been achieved. In fact, many studies have …

Circadian clocks are encoded by a transcription-translation feedback loop that aligns
energetic processes with the solar cycle. We show that genetic disruption of the clock …

We previously created two PER2:: LUCIFERASE (PER2:: LUC) circadian reporter knockin
mice that differ only in the Per2 3′-UTR region: Per2:: Luc, which retains the endogenous …

The generation of new adipocytes from precursor cells (adipogenesis) has implications for
systemic metabolism and is a commonly used model for studying the process of cell …

Normal physiological functions require a robust biological timer called the circadian clock.
When clocks are dysregulated, misaligned, or dampened, pathological consequences …

Endogenous circadian clocks regulate 24-h rhythms of physiology and behavior. Circadian
rhythm disruption (CRD) is suggested as a risk factor for inflammatory bowel disease …

Generalized anxiety and major depression have become increasingly common in the United
States, affecting 18.6 percent of the adult population. Mood disorders can be debilitating …

The egg-laying rate is an important indicator of egg production of laying ducks. Egg
production directly impacts the economic benefits of the duck industry. In order to obtain …

Obesity in women is increased by the loss of circulating estrogen after menopause. Shift
work, which disrupts circadian rhythms, also increases the risk for obesity. It is not known …