Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Background Impaired delivery of antifungals to hyphae within necrotic lesions is thought to
contribute to therapeutic failure in invasive pulmonary aspergillosis (IPA). We hypothesized …

Purpose The most important articles on infectious diseases (ID) pharmacotherapy published
in the peer-reviewed literature in 2015, as nominated and selected by panels of pharmacists …

The genus Malassezia comprises of extremely lipophilic yeasts secreting lipases as a vital
factor for survival. They are emerging as opportunistic pathogens in medical microbiology …

Recently, several randomized studies have been published that will shape treatment
decisions in the prevention and management of invasive mould infections. Liposomal …

Introduction: Pulmonary mold infections are caused by ubiquitous organisms found in soil,
water, and decaying vegetation, including Aspergillus spp., the Mucormycetes, hyaline …

Clinical and experimental data have shown discrepancies on the efficacy of combinations
between triazoles and echinocandins. In this study, anidulafungin plus posaconazole have …

Statistical figures represent that fungal infections are the major cause of thousands of deaths
each year. Despite the availability of treatment options invasive and systemic fungal …

The development of compounds capable of inhibiting glucan synthesis of the fungal cell wall
has been a milestone achievement in antifungal chemotherapy. Three classes of …

Pterostilbene is biologically classified as a phytoalexin, which is part of the plant's defence
system in response to pathogen infection. The present study is to identify the type of …