Alteration to the expression and activity of androgen receptor (AR) coregulators in prostate
cancer is an important mechanism driving disease progression and therapy resistance …

The critical regulatory mechanisms in numerous cellular pathways including cell survival
and DNA damage response mostly depend on phosphorylation and dephosphorylation of …

Cells decide whether to grow and divide by integrating internal and external signals. Non-
autonomous cell growth and proliferation occurs when microenvironmental signals from …

Wip1 is deregulated in numerous human malignancies. However, its roles in non‑small cell
lung cancer (NSCLC) remain unclear. In the current study, the expression of Wip1 was …

5.2 Abstract Degradation of 1, 25 (OH) 2D, the biologically active form of vitamin D, is driven
by the enzyme Cyp24a1 in target tissues, providing critical local control of 1, 25 (OH) 2D …