LncRNA PVT1 regulates chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR-488-3p

Y Li, S Li, Y Luo, Y Liu, N Yu - DNA and cell biology, 2017 - liebertpub.com
Long noncoding RNAs (lncRNAs) have been known to be involved in multiple diverse
diseases, including osteoarthritis (OA). The present study aims at exploring the biological …

[PDF][PDF] An osteoarthritis model of care should be a national priority for New Zealand

J Baldwin, A Briggs, W Bagg, P Larmer - The New Zealand Medical …, 2017 - nzmj.org.nz
Osteoarthritis is highly prevalent, disabling and costly to the person and the community. The
burden of this chronic condition is predicted to increase dramatically over the coming …

Osteoarthritis management: time to change the deck

DJ Hunter - journal of orthopaedic & sports physical therapy, 2017 - jospt.org
This Viewpoint highlights the shortcomings of existing osteoarthritis (OA) clinical practices
and emphasizes the opportunity that can come about by virtue of adherence to appropriate …

[HTML][HTML] Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface

SA Flowers, A Zieba, J Örnros, C Jin, O Rolfson… - Scientific reports, 2017 - nature.com
Lubricin, a heavily O-glycosylated protein, is essential for boundary lubrication of articular
cartilage. Strong surface adherence of lubricin is required given the extreme force it must …

[HTML][HTML] Effect of a model consultation informed by guidelines on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary …

KP Jordan, JJ Edwards, M Porcheret, EL Healey… - Osteoarthritis and …, 2017 - Elsevier
Objective To determine the effect of a model osteoarthritis (OA) consultation (MOAC)
informed by National Institute for Health and Care Excellence (NICE) recommendations …

Gaps in appropriate use of treatment strategies in osteoarthritis

KD Allen, YM Golightly, DK White - Best Practice & Research Clinical …, 2017 - Elsevier
Optimal management of osteoarthritis (OA) requires a combination of therapies, with
behavioral (eg, exercise and weight management) and rehabilitative components at the …

Are you managing osteoarthritis appropriately?

DJ Hunter, JL Bowden - Nature Reviews Rheumatology, 2017 - nature.com
For patients with osteoarthritis, the current palliative approach of analgesic prescription
followed by joint replacement is often inappropriate. Instead, care should be tailored to the …

It is time to stop meniscectomy

EM Roos, JB Thorlund - British Journal of Sports Medicine, 2017 - bjsm.bmj.com
Recently, the New York Times asked why 'useless' surgery is still popular. 1 In this editorial
we outline three factors that likely promote continuing use of arthroscopic partial …

Musculoskeletal health: addressing the leading causes of disability

KD Allen - North Carolina Medical Journal, 2017 - ncmedicaljournal.com
Musculoskeletal conditions are not only the most common group of chronic health problems
in our country, but they have a profound impact on critical domains of health including pain …

Artroseskole i primærhelsetjenesten-Smerte og fysisk funksjon hos artrosepasienter etter artroseskole i primærhelsetjenesten

LF Martinsen - 2017 - duo.uio.no
Formål: Å undersøke om 12 ukers artroseskole (et tverrfaglig behandlingstilbud med
undervisning og øvelser i primærhelsetjenesten) fører til endring i selvrapportert smerte og …