Epigenetic alterations in rheumatoid arthritis fibroblast-like synoviocytes

KM Doody, N Bottini, GS Firestein - Epigenomics, 2017 - Taylor & Francis
Rheumatoid arthritis is an immune-mediated disease that primarily affects diarthrodial joints.
Susceptibility and severity of this disease are influenced by nongenetic factors, such as …

MicroRNAs and bioactive compounds on TLR/MAPK signaling in rheumatoid arthritis

S Sujitha, M Rasool - Clinica Chimica Acta, 2017 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune mediated joint disease with severe
complications affecting 1% of the population worldwide. Although the exact mechanism …

[HTML][HTML] MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

M Kurowska-Stolarska, S Alivernini, EG Melchor… - Nature …, 2017 - nature.com
Current treatments for rheumatoid arthritis (RA) do not reverse underlying aberrant immune
function. A genetic predisposition to RA, such as HLA-DR4 positivity, indicates that dendritic …

Serum miR-210 and miR-155 expression levels as novel biomarkers for rheumatoid arthritis diagnosis

RS Abdul-Maksoud, AM Sediq… - British Journal of …, 2017 - Taylor & Francis
Background: MicroRNAs play a crucial role in the regulation of immune response. We
hypothesised roles for serum miR-210 and miR-155 in the diagnosis of rheumatoid arthritis …

MiR-650 inhibits proliferation, migration and invasion of rheumatoid arthritis synovial fibroblasts by targeting AKT2

X Xu, H Chen, Q Zhang, J Xu, Q Shi, M Wang - Biomedicine & …, 2017 - Elsevier
Background and objectives This study was aimed to investigate the effects of miR-650 on
the proliferation, migration, invasion and apoptosis of rheumatoid arthritis synovial …

Epigenetic aspects of rheumatoid arthritis: contribution of non-coding RNAs

B Kolarz, M Majdan - Seminars in arthritis and rheumatism, 2017 - Elsevier
Since microRNA was discovered in the late 1990s the role of non-coding RNAs in the
regulation of cellular processes has been confirmed. Intensive researches have revealed a …

[HTML][HTML] Survivin controls biogenesis of microRNA in smokers: A link to pathogenesis of rheumatoid arthritis

KME Andersson, M Turkkila, MC Erlandsson… - … et Biophysica Acta (BBA …, 2017 - Elsevier
MicroRNAs (miRs) represent a part of epigenetic control of autoimmunity gaining increasing
attention in rheumatoid arthritis (RA). Since cigarette smoking plays important role in RA …

Role of MicroRNAs in rheumatoid arthritis

M Birlik, A Koçak, D Harmancı - New Developments in the …, 2017 - books.google.com
Rheumatoid arthritis (RA) is a common autoimmune disease. The hallmarks of RA are
synovial inflammation and hyperplasia, autoantibody production, systemic features, and …

The role of genetic analysis for predicting outcome of rheumatoid arthritis

M Chaudhry, AG Wilson - Expert Review of Molecular Diagnostics, 2017 - Taylor & Francis
ABSTRACT Introduction: Rheumatoid Arthritis (RA) varies from a mild to a severe,
unremitting illness characterized by uncontrolled inflammation with consequent damage to …

[PDF][PDF] Investigating the Role of miRNA-34 family in human thyroid cancer

H Maroof - 2017 - core.ac.uk
Thyroid cancer is the most rampant endocrine malignancy accounting for> 80% of endocrine
malignancy and 1.8% of all recently distinguished cancer reports. The most important risk …