Outer membrane vesicles harboring modified lipid A moiety augment the efficacy of an influenza vaccine exhibiting reduced endotoxicity in a mouse model
TY Lee, CU Kim, EH Bae, SH Seo, DG Jeong… - Vaccine, 2017 - Elsevier
Influenza is an acute respiratory disease and a major health problem worldwide. Since
mucosal immunity plays a critical role in protection against influenza virus infection, mucosal …
mucosal immunity plays a critical role in protection against influenza virus infection, mucosal …
Nontoxic outer membrane vesicles efficiently increase the efficacy of an influenza vaccine in mice and ferrets
In this study, we developed a further-modified outer membrane vesicle (fmOMV) from the
ΔmsbB/ΔpagP mutant of Escherichia coli transformed with the plasmid, pLpxF, in order to …
ΔmsbB/ΔpagP mutant of Escherichia coli transformed with the plasmid, pLpxF, in order to …
Novel Lipid A Structures for Adjuvant Discovery and Development
KA Gregg - 2017 - search.proquest.com
There is an urgent need to develop effective immunizations against infectious diseases that
continue to be a major cause of morbidity and mortality worldwide. Modern subunit vaccines …
continue to be a major cause of morbidity and mortality worldwide. Modern subunit vaccines …