[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

MH Shamji, SR Durham - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Applications and mechanisms of immunotherapy in allergic rhinitis and asthma

JH Kappen, SR Durham, HI Veen… - … in respiratory disease, 2017 - journals.sagepub.com
Clinical and immunologic tolerance are hallmarks of successful allergen immunotherapy
(AIT). Clinical benefits such as reduced symptoms, pharmacotherapy intake and …

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper

MH Shamji, JH Kappen, M Akdis, E Jensen‐Jarolim… - Allergy, 2017 - Wiley Online Library
Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …

Novel approaches and perspectives in allergen immunotherapy

HJ Hoffmann, E Valovirta, O Pfaar, P Moingeon… - Allergy, 2017 - Wiley Online Library
In this review, we report on relevant current topics in allergen immunotherapy (AIT) which
were broadly discussed during the first Aarhus Immunotherapy Symposium (Aarhus …

[HTML][HTML] Oral immunotherapy combined with omalizumab for high–risk cow's milk allergy: A randomized controlled trial

M Takahashi, K Soejima, S Taniuchi, Y Hatano… - Scientific reports, 2017 - nature.com
We evaluated the efficacy and safety of oral immunotherapy (OIT) combined with 24 weeks
of omalizumab (OMB) at inducing desensitization in children with cow's milk allergy (CM) …

[HTML][HTML] Subcutaneous and sublingual immunotherapy in allergic asthma in children

S Tsabouri, A Mavroudi, G Feketea… - Frontiers in Pediatrics, 2017 - frontiersin.org
This review presents up-to-date understanding of immunotherapy in the treatment of
children with allergic asthma. The principal types of allergen immunotherapy (AIT) are …

[HTML][HTML] A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification

J Arebro, S Ekstedt, E Hjalmarsson, O Winqvist… - Scientific Reports, 2017 - nature.com
A re-examination of former concepts is required to meet today's medical challenges in
allergic rhinitis. Previously, neutrophils have been treated as a relatively homogenous cell …

[HTML][HTML] Update on biomarkers to monitor clinical efficacy response during and post treatment in allergen immunotherapy

L Kouser, J Kappen, RP Walton, MH Shamji - Current treatment options in …, 2017 - Springer
Opinion statement Allergen immunotherapy (AIT) is an immune modulating treatment for
allergic diseases. Although highly effective, some patients do not respond to the treatment …

Immunotherapy for cow's milk allergy

S Taniuchi, M Takahashi, K Soejima… - Human Vaccines & …, 2017 - Taylor & Francis
Oral immunotherapy (OIT) is used regularly for young children with cow's milk (CM) allergy
and has been shown to be effective in several studies. However, adverse events occur …

Nanoparticle–allergen complexes for allergen immunotherapy

G Di Felice, P Colombo - International journal of nanomedicine, 2017 - Taylor & Francis
Allergen-specific immunotherapy was introduced in clinical settings more than 100 years
ago. It remains the only curative approach to treating allergic disorders that ameliorates …