Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans

Y Wang, H Liu, Z Sun - Biological Reviews, 2017 - Wiley Online Library
Organisms can change their physiological/behavioural traits to adapt and survive in
changed environments. However, whether these acquired traits can be inherited across …

[HTML][HTML] Metabolic inputs into the epigenome

U Sharma, OJ Rando - Cell metabolism, 2017 - cell.com
A number of molecular pathways play key roles in transmitting information in addition to the
genomic sequence—epigenetic information—from one generation to the next. However, so …

Allelic reprogramming of 3D chromatin architecture during early mammalian development

Z Du, H Zheng, B Huang, R Ma, J Wu, X Zhang, J He… - Nature, 2017 - nature.com
In mammals, chromatin organization undergoes drastic reprogramming after fertilization.
However, the three-dimensional structure of chromatin and its reprogramming in …

[HTML][HTML] Chromatin states in mouse sperm correlate with embryonic and adult regulatory landscapes

YH Jung, MEG Sauria, X Lyu, MS Cheema, J Ausio… - Cell reports, 2017 - cell.com
The mammalian sperm genome is thought to lack substantial information for the regulation
of future expression after fertilization. Here, we show that most promoters in mouse sperm …

Germ line–inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition

F Zenk, E Loeser, R Schiavo, F Kilpert, O Bogdanović… - Science, 2017 - science.org
Gametes carry parental genetic material to the next generation. Stress-induced epigenetic
changes in the germ line can be inherited and can have a profound impact on offspring …

[HTML][HTML] The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

C Ernst, DT Odom, C Kutter - Nature communications, 2017 - nature.com
Transposable elements (TEs) contribute to the large amount of repetitive sequences in
mammalian genomes and have been linked to species-specific genome innovations by …

[HTML][HTML] Epigenetic considerations in aquaculture

MR Gavery, SB Roberts - PeerJ, 2017 - peerj.com
Epigenetics has attracted considerable attention with respect to its potential value in many
areas of agricultural production, particularly under conditions where the environment can be …

Epigenetics in fish gametes and early embryo

C Labbé, V Robles, MP Herraez - Aquaculture, 2017 - Elsevier
The spermatozoa and oocyte are very specialized cells which possess the unique ability to
fuse and to produce an embryo. This embryo will develop into a mature organism capable of …

Mitotic chromosome assembly despite nucleosome depletion in Xenopus egg extracts

K Shintomi, F Inoue, H Watanabe, K Ohsumi, M Ohsugi… - Science, 2017 - science.org
The nucleosome is the fundamental structural unit of eukaryotic chromatin. During mitosis,
duplicated nucleosome fibers are organized into a pair of rod-shaped structures …

Low-dose ionizing radiation exposure, oxidative stress and epigenetic programing of health and disease

S Tharmalingam, S Sreetharan… - Radiation …, 2017 - meridian.allenpress.com
Ionizing radiation exposure from medical diagnostic imaging has greatly increased over the
last few decades. Approximately 80% of patients who undergo medical imaging are …