Nanoparticles as safe and effective delivery systems of antifungal agents: Achievements and challenges

GM Soliman - International journal of pharmaceutics, 2017 - Elsevier
Invasive fungal infections are becoming a major health concern in several groups of patients
leading to severe morbidity and mortality. Moreover, cutaneous fungal infections are a major …

Niosomes: a review of their structure, properties, methods of preparation, and medical applications

PL Yeo, CL Lim, SM Chye, APK Ling, RY Koh - Asian Biomedicine, 2017 - sciendo.com
Target-specific drug-delivery systems for the administration of pharmaceutical compounds
enable the localization of drugs to diseased sites. Various types of drug-delivery systems …

[HTML][HTML] Ultrasound processed nanoemulsion: A comparative approach between resveratrol and resveratrol cyclodextrin inclusion complex to study its binding …

R Kumar, K Kaur, S Uppal, SK Mehta - Ultrasonics sonochemistry, 2017 - Elsevier
Resveratrol is a naturally occurring therapeutic molecule used for treatment of diseases
caused by oxidative stress. This investigation elucidates the advantages of fabrication of …

Maximizing the therapeutic efficacy of imatinib mesylate–loaded niosomes on human colon adenocarcinoma using Box-Behnken design

MA Kassem, HS El-Sawy, FI Abd-Allah… - Journal of …, 2017 - Elsevier
This research purposed to formulate an optimized imatinib mesylate (IM)–loaded niosomes
to improve its chemotherapeutic efficacy. The influence of 3 formulation factors on niosomal …

Design and evaluation of proniosomes as a carrier for ocular delivery of lomefloxacin HCl

RM Khalil, GA Abdelbary, M Basha… - Journal of liposome …, 2017 - Taylor & Francis
The current investigation aims to develop and evaluate novel ocular proniosomal gels of
lomefloxacin HCl (LXN); in order to improve its ocular bioavailability for the management of …

Enhancement of lomefloxacin Hcl ocular efficacy via niosomal encapsulation: in vitro characterization and in vivo evaluation

RM Khalil, GA Abdelbary, M Basha… - Journal of liposome …, 2017 - Taylor & Francis
The aim of this study is to develop and evaluate niosomal dispersions loaded with the
hydrophilic drug; lomefloxacin Hcl (LXN) for the management of ocular bacterial …

Optimized mucoadhesive coated niosomes as a sustained oral delivery system of famotidine

ALZM Khalifa, BK Abdul Rasool - Aaps Pharmscitech, 2017 - Springer
The objective of this study is to develop an oral formulation of famotidine niosomes coated
with a mucoadhesive polymer, chitosan. Famotidine (FMT) has low oral bioavailability of 40 …

Mucoadhesive niosomal in situ gel for ocular tissue targeting: in vitro and in vivo evaluation of lomefloxacin hydrochloride

A Abdelbary, HF Salem, RA Khallaf… - Pharmaceutical …, 2017 - Taylor & Francis
Eradication of ophthalmic infections depends on increasing transcorneal permeation and
localizing antibiotics at ocular surface. This study aimed at formulating lomefloxacin HCl (LF) …

In vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration

HO Ammar, M Haider, M Ibrahim, NM El Hoffy - Drug delivery, 2017 - Taylor & Francis
Diltiazem hydrochloride (DTZ) is a calcium channel antagonist depicted by extensive first
pass metabolism and low oral bioavailability. The aim of this work was to develop niosomes …

Enhanced oral bioavailability and sustained delivery of glimepiride via niosomal encapsulation: in-vitro characterization and in-vivo evaluation

AM Mohsen, MM AbouSamra… - Drug Development and …, 2017 - Taylor & Francis
This study was designed to investigate the potency of niosomes, for glimepiride (GLM)
encapsulation, aiming at enhancing its oral bioavailability and hypoglycemic efficacy …