[HTML][HTML] The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment

MJ Geerlings, EK de Jong, AI den Hollander - Molecular immunology, 2017 - Elsevier
Age-related macular degeneration (AMD) is a progressive retinal disease and the major
cause of irreversible vision loss in the elderly. Numerous studies have found both common …

Haemolytic uraemic syndrome

D Karpman, S Loos, R Tati… - Journal of internal …, 2017 - Wiley Online Library
Haemolytic uraemic syndrome (HUS) is defined by the simultaneous occurrence of
nonimmune haemolytic anaemia, thrombocytopenia and acute renal failure. This leads to …

Hemolytic uremic syndrome in pregnancy and postpartum

A Bruel, D Kavanagh, M Noris, Y Delmas… - Clinical Journal of the …, 2017 - journals.lww.com
Background Pregnancy is associated with various forms of thrombotic microangiopathy,
including hemolytic uremic syndrome. A previous small French study suggested that …

Atypical hemolytic uremic syndrome in the setting of complement-amplifying conditions: case reports and a review of the evidence for treatment with eculizumab

A Asif, A Nayer, CS Haas - Journal of nephrology, 2017 - Springer
Atypical hemolytic uremic syndrome (aHUS) is a rare, genetic, progressive, life-threatening
form of thrombotic microangiopathy (TMA) predominantly caused by dysregulation of the …

[HTML][HTML] Atypical hemolytic uremic syndrome: a brief review

K Zhang, Y Lu, KT Harley, MH Tran - Hematology reports, 2017 - ncbi.nlm.nih.gov
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by the triad of
microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. The …

Renal dysfunction following bone marrow transplantation

S Kemmner, M Verbeek, U Heemann - Journal of nephrology, 2017 - Springer
Acute kidney injury and long-term renal dysfunction are common problems following bone
morrow transplantation (BMT) and highly related to mortality. The frequency and risk of renal …

Life‐threatening pregnancy‐associated atypical haemolytic uraemic syndrome and its response to eculizumab

R Gately, A San, J Kurtkoti, A Parnham - Nephrology, 2017 - Wiley Online Library
Pregnancy‐associated atypical haemolytic uraemic syndrome (P‐aHUS) is a rare,
potentially lethal condition that can complicate pregnancy in up to 1 in 25 000 cases. Without …

Rare genetic variants in Shiga toxin-associated haemolytic uraemic syndrome: genetic analysis prior to transplantation is essential

F Dowen, K Wood, AL Brown, J Palfrey… - Clinical Kidney …, 2017 - academic.oup.com
We present a case of haemolytic uraemic syndrome (HUS) in a 16-year-old female with
serological evidence of acute Escherichia coli O157: H7 infection. She progressed to …

Atypical hemolytic uremic syndrome

Y Yoshida, H Kato, M Nangaku - Renal Replacement Therapy, 2017 - Springer
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA)
characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal …

Eculizumab in a child with atypical haemolytic uraemic syndrome and haemophagocytic lymphohistiocytosis triggered by cytomegalovirus infection

GM Fraga-Rodriguez, S Brió-Sanagustin… - Case …, 2017 - casereports.bmj.com
We present the case of a 21-month-old girl with two rare and life-threatening conditions,
atypical haemolytic uraemic syndrome (aHUS) and haemophagocytic lymphohistiocytosis …