Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability

M Boretto, B Cox, M Noben, N Hendriks… - …, 2017 - journals.biologists.com
The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …

Tissue-specific ablation of the LIF receptor in the murine uterine epithelium results in implantation failure

JG Cheng, G Rosario, TV Cohen, J Hu… - Endocrinology, 2017 - academic.oup.com
The cytokine leukemia inhibitory factor (LIF) is essential for rendering the uterus receptive for
blastocyst implantation. In mice, LIF receptor expression (LIFR) is largely restricted to the …

LKB1 as a tumor suppressor in uterine cancer: Mouse models and translational studies

CG Peña, DH Castrillón - Molecular Genetics of Endometrial Carcinoma, 2017 - Springer
The LKB1 tumor suppressor was identified in 1998 as the gene mutated in the Peutz–
Jeghers Syndrome (PJS), a hereditary cancer predisposition characterized by …

[PDF][PDF] Gynecological tissue homeostasis and tumorigenesis studies using mouse models

A Guimaraes-Young - 2017 - iro.uiowa.edu
Gynecological cancers present a tremendous disease burden worldwide. Endometrial
cancer, the most common gynecological malignancy, is predominantly a disease of …

Cyclin B1 mediates the effect of UCHL1 in promoting cell cycle progression in uterine papillary serous carcinoma

SY Kwan - 2017 - digitalcommons.library.tmc.edu
Uterine papillary serous carcinoma (UPSC) is an aggressive form of endometrial cancer with
poor survival rates and a high risk of recurrence. The rarity of UPSC poses challenges to the …

[引用][C] Elucidating the Role of MMS22L on Uterine Epithelium

Y Hadjiyannis - 2017 - The Ohio State University