Abstract Purpose of Review The purposes of this review were as follows: first, to provide an
overview of the gut microbiota and its interactions with the gut and the central nervous …

While modernization has dramatically increased lifespan, it has also witnessed the nature of
stress has changed dramatically. Chronic stress result failures of homeostasis and thus lead …

It has become increasingly clear that the gut microbiota influences not only gastrointestinal
physiology but also central nervous system (CNS) function by modulating signalling …

The topic of gut microbiota is currently attracting considerable interest as a potential factor in
Alzheimer's disease (AD). However, the extent and time course of alterations in the gut …

Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …

Accumulating evidence suggests that the gut microbiota–brain axis plays a role in the
pathogenesis of depression, thereby contributing to the antidepressant actions of certain …

Intestinal microbes are an important system in the human body, with significant effects on
behavior. An increasing body of research indicates that intestinal microbes affect brain …

Major depressive disorder (MDD) and other mood disorders remain difficult to effectively
treat, and innovative interventions and therapeutic targets are needed. Psychological …

Inflammasome activation in the central nervous system occurs in both health and disease.
Inflammasomes are cytosolic protein complexes that sense specific infectious or host stimuli …

Depression is a common, severe and chronic psychiatric disease. Although the currently
available antidepressants have been used in the treatment of depression, their beneficial …