Endothelial dysfunction and vascular disease–a 30th anniversary update
PM Vanhoutte, H Shimokawa, M Feletou… - Acta …, 2017 - Wiley Online Library
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …
Spotlight on anti‐CGRP monoclonal antibodies in migraine: The clinical evidence to date
L Pellesi, S Guerzoni, LA Pini - Clinical pharmacology in drug …, 2017 - Wiley Online Library
Migraine, a common neurovascular brain disorder, represents a severe and widespread
health problem; along with medication‐induced (medication‐overuse) headache, it is the …
health problem; along with medication‐induced (medication‐overuse) headache, it is the …
Tail‐cuff technique and its influence on central blood pressure in the mouse
E Wilde, AA Aubdool, P Thakore… - Journal of the …, 2017 - Am Heart Assoc
Background Reliable measurement of blood pressure in conscious mice is essential in
cardiovascular research. Telemetry, the “gold‐standard” technique, is invasive and …
cardiovascular research. Telemetry, the “gold‐standard” technique, is invasive and …
A novel α-calcitonin gene-related peptide analogue protects against end-organ damage in experimental hypertension, cardiac hypertrophy, and heart failure
AA Aubdool, P Thakore, F Argunhan, SJ Smillie… - Circulation, 2017 - Am Heart Assoc
Background: Research into the therapeutic potential of α-calcitonin gene–related peptide (α-
CGRP) has been limited because of its peptide nature and short half-life. Here, we evaluate …
CGRP) has been limited because of its peptide nature and short half-life. Here, we evaluate …
CGRP monoclonal antibodies for migraine: rationale and progress
Calcitonin gene-related peptide (CGRP), a neuropeptide abundant in the trigeminal system
and widely expressed in both the peripheral and central nervous systems, has recently …
and widely expressed in both the peripheral and central nervous systems, has recently …
Olcegepant blocks neurogenic and non‐neurogenic CGRPergic vasodepressor responses and facilitates noradrenergic vasopressor responses in pithed rats
VH Avilés‐Rosas, E Rivera‐Mancilla… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Olcegepant (BIBN4096BS) is a selective non‐peptide CGRP
receptor antagonist with acute antimigraine properties. Since systemic vascular tone is …
receptor antagonist with acute antimigraine properties. Since systemic vascular tone is …
Calcitonin gene-related peptide receptor agonism: a double-edged sword?
AHJ Danser, A MaassenVanDenBrink - Circulation, 2017 - Am Heart Assoc
Calcitonin Gene-Related Peptide Receptor Agonism | Circulation Science Volunteer Warning
signs SearchSearch Advanced Search Donate Circulation logo Hello Guest! MY ALERTS …
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Lessons learned from CGRP mutant mice
Calcitonin gene‐related peptide (CGRP) plays a pivotal role in migraine pathogenesis, and
the development of CGRP‐mutant mouse models has been fruitful in the ongoing …
the development of CGRP‐mutant mouse models has been fruitful in the ongoing …
The role of perivascular adipose tissue-derived sensory nerves in influencing vascular regulation
Sensory nerves comprising C and Ad fibres are commonly found surrounding vascular
tissues. They contain and release potent biologically active peptides of which substance P …
tissues. They contain and release potent biologically active peptides of which substance P …
CGRP als therapeutisches Ziel in der Therapie von primären Kopfschmerzen
L Neeb, U Reuter, H Israel - Nervenheilkunde, 2017 - thieme-connect.com
Calcitonin gene related peptide (CGRP) übernimmt eine wichtige Rolle in der
Pathophysiologie von primären Kopfschmerzerkrankungen in seiner Funktion als potenter …
Pathophysiologie von primären Kopfschmerzerkrankungen in seiner Funktion als potenter …