Conspectus Inter-or intramolecular hydroamination reactions are a paradigmatic example of
modern sustainable organic chemistry, as they are a catalytic, 100% atom-economical, and …

Rationale: Deep vein thrombosis (DVT) and its complication pulmonary embolism have high
morbidity reducing quality of life and leading to death. Cellular mechanisms of DVT initiation …

Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of
recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the …

Chronic hepatitis C virus (HCV) infection causes severe liver disease and affects ca. 146
million individuals. Novel directly acting antivirals targeting HCV have revolutionized …

Histamine mediates a wide range of cellular responses, including allergic and inflammatory
reactions, gastric acid secretion, and neurotransmission in the central nervous system …

Acute myeloid leukemia (AML) consists in a cancer of early hematopoietic cells arising in the
bone marrow, most often of those cells that would turn into white blood cells (except …

Mesenchymal stem cells (MSCs) in ossification of the posterior longitudinal ligament (OPLL)
patients have a high propensity toward osteogenesis. Histamine receptor H2 (H2R) …

In the clinical and pharmacological fields, there is a need for the production of tissue‐
engineered small‐diameter blood vessels. We have demonstrated previously that the …

The degradation of histamine catalyzed by the SAM-dependent histamine N-
methyltransferase (HNMT) is critically important for the maintenance of neurological …

The histaminergic system modulates numerous physiological functions such as
wakefulness, circadian rhythm, feeding, and thermoregulation. However, it is not yet known if …