The IGF1-PI3K-Akt signaling pathway in mediating exercise-induced cardiac hypertrophy and protection

KL Weeks, BC Bernardo, JYY Ooi, NL Patterson… - … disease prevention and …, 2017 - Springer
Regular physical activity or exercise training can lead to heart enlargement known as
cardiac hypertrophy. Cardiac hypertrophy is broadly defined as an increase in heart mass. In …

Skeletal muscle inflammation and atrophy in heart failure

KJ Lavine, OL Sierra - Heart failure reviews, 2017 - Springer
Heart failure represents a systemic disease with profound effects on multiple peripheral
tissues including skeletal muscle. Within the context of heart failure, perturbations in skeletal …

Overexpression of gremlin1 in mesenchymal stem cells improves hindlimb ischemia in mice by enhancing cell survival

Q Xiang, D Hong, Y Liao, Y Cao, M Liu… - Journal of Cellular …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) are a promising cell resource for the treatment of ischemic
diseases, partially through paracrine effects. One of the major obstacles of MSC treatment is …

Fetal origins of adult cardiac disease: a novel approach to prevent fetal growth restriction induced cardiac dysfunction using insulin like growth factor

T Alsaied, K Omar, JF James, RB Hinton… - Pediatric …, 2017 - nature.com
Background: Fetal growth restriction (FGR) is a risk factor for adult cardiovascular disease.
Intraplacental gene transfer of human insulin-like growth factor-1 (IGF-1) corrects birth …

羊奶及其制品的研究进展

高佳媛, 邵玉宇, 王毕妮, 张富新 - 中国乳品工业, 2017 - cqvip.com
羊奶及其制品的研究进展-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车 充值 客服
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SOCS2 exacerbates myocardial injury induced by ischemia/reperfusion in diabetic mice and H9c2 cells through inhibiting the JAK-STAT-IGF-1 pathway

M Sheng, Z Huang, L Pan, M Yu, C Yi, L Teng, L He… - Life sciences, 2017 - Elsevier
Aims This study aimed to investigate potential candidates and molecular mechanisms of
myocardial ischemia/reperfusion (I/R) injury (MIRI) in type 2 diabetes mellitus. Main methods …

[图书][B] Study and therapeutic interference of T cell function in pressure overload-induced heart failure

E Martini - 2017 - search.proquest.com
Heart failure (HF), which is the end-stage of pathological cardiac hypertrophy, is a leading
cause of hospitalization and mortality. Cardiac remodeling, hypertrophy and fibrosis …

Improving stem cell engraftment to enhance functional efficacy in cardiovascular disease: where are we now?

A Thi-Van Bui, TLB Pham… - … Research and Therapy, 2017 - bmrat.biomedpress.org
Stem cell therapy is a promising therapy for repairing damaged tissue. A growing body of
research shows that stem cells work effectively in several diseases such as cardiovascular …