Emerging properties and functional consequences of noncoding transcription
R Ard, RC Allshire, S Marquardt - Genetics, 2017 - academic.oup.com
Eukaryotic genomes are rich in transcription units encoding “long noncoding
RNAs”(lncRNAs). The purpose of all this transcription is unclear since most lncRNAs are …
RNAs”(lncRNAs). The purpose of all this transcription is unclear since most lncRNAs are …
Noncoding RNA surveillance: the ends justify the means
Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded,
defective, and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess …
defective, and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess …
Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo
Here we employ a set of RNA Polymerase II (Pol II) activity mutants to determine the
consequences of increased or decreased Pol II catalysis on gene expression in …
consequences of increased or decreased Pol II catalysis on gene expression in …
Similarity-based segmentation of multi-dimensional signals
The segmentation of time series and genomic data is a common problem in computational
biology. With increasingly complex measurement procedures individual data points are …
biology. With increasingly complex measurement procedures individual data points are …
Yeast RNA-binding protein Nab3 regulates genes involved in nitrogen metabolism
J Merran, JL Corden - Molecular and cellular biology, 2017 - Taylor & Francis
Termination of Saccharomyces cerevisiae RNA polymerase II (Pol II) transcripts occurs
through two alternative pathways. Termination of mRNAs is coupled to cleavage and …
through two alternative pathways. Termination of mRNAs is coupled to cleavage and …
From transcriptional complexity to cellular phenotypes: Lessons from yeast
V Pelechano - Yeast, 2017 - Wiley Online Library
Pervasive transcription has been reported in many eukaryotic organisms, revealing a highly
interleaved transcriptome organization that involves thousands of coding and non‐coding …
interleaved transcriptome organization that involves thousands of coding and non‐coding …
Understanding protein-DNA binding events
AS Kiesel - 2017 - edoc.ub.uni-muenchen.de
DNA binding proteins regulate essential biological processes such as DNA replication,
transcription, repair, and splicing. Transcription factors (TFs) are in the focus of this work …
transcription, repair, and splicing. Transcription factors (TFs) are in the focus of this work …