WFUMB guidelines and recommendations on the clinical use of ultrasound elastography: Part 5. Prostate

RG Barr, D Cosgrove, M Brock, V Cantisani… - Ultrasound in medicine …, 2017 - Elsevier
Abstract The World Federation for Ultrasound in Medicine and Biology (WFUMB) has
produced guidelines for the use of elastography techniques, including basic science, breast …

[HTML][HTML] Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study

HU Ahmed, AES Bosaily, LC Brown, R Gabe, R Kaplan… - The Lancet, 2017 - thelancet.com
Background Men with high serum prostate specific antigen usually undergo transrectal
ultrasound-guided prostate biopsy (TRUS-biopsy). TRUS-biopsy can cause side-effects …

Tumour heterogeneity poses a significant challenge to cancer biomarker research

K Cyll, E Ersvær, L Vlatkovic, M Pradhan… - British journal of …, 2017 - nature.com
Background: The high degree of genomic diversity in cancer represents a challenge for
identifying objective prognostic markers. We aimed to examine the extent of tumour …

T2-weighted MRI-derived textural features reflect prostate cancer aggressiveness: preliminary results

G Nketiah, M Elschot, E Kim, JR Teruel… - European …, 2017 - Springer
Purpose To evaluate the diagnostic relevance of T2-weighted (T2W) MRI-derived textural
features relative to quantitative physiological parameters derived from diffusion-weighted …

Cholesterol uptake and regulation in high-grade and lethal prostate cancers

KH Stopsack, TA Gerke, O Andrén… - …, 2017 - academic.oup.com
Lethal prostate cancers have higher expression of squalene monooxygenase (SQLE), the
second rate-limiting enzyme of cholesterol synthesis. Preclinical studies suggested that …

Prognostic utility of a new mRNA expression signature of Gleason score

JA Sinnott, SF Peisch, S Tyekucheva, T Gerke… - Clinical Cancer …, 2017 - AACR
Purpose: Gleason score strongly predicts prostate cancer mortality; however, scoring varies
among pathologists, and many men are diagnosed with intermediate-risk Gleason score 7 …

Prognostic value of the new grade groups in prostate cancer: a multi-institutional European validation study

R Mathieu, M Moschini, B Beyer, KM Gust… - Prostate cancer and …, 2017 - nature.com
Background: We aimed to assess the prognostic relevance of the new Grade Groups in
Prostate Cancer (PCa) within a large cohort of European men treated with radical …

Wisteria floribunda Agglutinin and Its Reactive-Glycan-Carrying Prostate-Specific Antigen as a Novel Diagnostic and Prognostic Marker of Prostate Cancer

K Hagiwara, Y Tobisawa, T Kaya, T Kaneko… - International journal of …, 2017 - mdpi.com
Wisteria floribunda agglutinin (WFA) preferably binds to LacdiNAc glycans, and its reactivity
is associated with tumor progression. The aim of this study to examine whether the serum …

Limitations in predicting organ confined prostate cancer in patients with Gleason pattern 4 on biopsy: implications for active surveillance

N Perlis, R Sayyid, A Evans, T Van Der Kwast, A Toi… - The Journal of …, 2017 - Elsevier
Purpose In prostate cancer biopsy Gleason score predicts stage and helps determine active
surveillance suitability. Evidence suggests that small incremental differences in the …

Diagnostic value of integrated PET/MRI for detection and localization of prostate cancer: Comparative study of multiparametric MRI and PET/CT

MS Lee, JY Cho, SY Kim, GJ Cheon… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose To evaluate the diagnostic value of integrated positron emission
tomography/magnetic resonance imaging (PET/MRI) compared with conventional …