[HTML][HTML] Ribosomal protein S6 phosphorylation is involved in novelty-induced locomotion, synaptic plasticity and mRNA translation
The phosphorylation of the ribosomal protein S6 (rpS6) is widely used to track neuronal
activity. Although it is generally assumed that rpS6 phosphorylation has a stimulatory effect …
activity. Although it is generally assumed that rpS6 phosphorylation has a stimulatory effect …
Heterozygous Gnal mice are a novel animal model with which to study dystonia pathophysiology
Dystonia is a movement disorder characterized by sustained or intermittent muscle
contractions and its pathophysiological mechanisms are still poorly understood. Dominant …
contractions and its pathophysiological mechanisms are still poorly understood. Dominant …
[HTML][HTML] Development of novel biosensors to study receptor-mediated activation of the G-protein α subunits Gs and Golf
Gα s (G s) and Gα olf (G olf) are highly homologous G-protein α subunits that activate
adenylate cyclase, thereby serving as crucial mediators of intracellular signaling. Because of …
adenylate cyclase, thereby serving as crucial mediators of intracellular signaling. Because of …
[HTML][HTML] Striatal Gαolf/cAMP Signal-Dependent Mechanism to Generate Levodopa-Induced Dyskinesia in Parkinson's Disease
S Goto - Frontiers in cellular neuroscience, 2017 - frontiersin.org
The motor symptoms of Parkinson's disease (PD) result from striatal dopamine (DA)
deficiency due to a progressive degeneration of nigral dopaminergic cells. Although DA …
deficiency due to a progressive degeneration of nigral dopaminergic cells. Although DA …
[HTML][HTML] Dopamine-Induced Changes in Gαolf Protein Levels in Striatonigral and Striatopallidal Medium Spiny Neurons Underlie the Genesis of l-DOPA-Induced …
R Morigaki, S Okita, S Goto - Frontiers in cellular neuroscience, 2017 - frontiersin.org
The dopamine precursor, l-3, 4-dihydroxyphenylalanine (l-DOPA), exerts powerful
therapeutic effects but eventually generates l-DOPA-induced dyskinesia (LID) in patients …
therapeutic effects but eventually generates l-DOPA-induced dyskinesia (LID) in patients …
Conditional deletion of Ric-8b in olfactory sensory neurons leads to olfactory impairment
CF Machado, MH Nagai, CS Lyra… - Journal of …, 2017 - Soc Neuroscience
The olfactory system can discriminate a vast number of odorants. This ability derives from
the existence of a large family of odorant receptors expressed in the cilia of the olfactory …
the existence of a large family of odorant receptors expressed in the cilia of the olfactory …
Functional and Structural Insights into the First and Second Intracellular Domains for D1-Class Dopaminergic Receptors
B Zhang - 2017 - ruor.uottawa.ca
Previous studies have shown that the subtype-specific pharmacological properties of D1-
class receptors (D1R and D5R) can be attributed to their third intracellular domain and C …
class receptors (D1R and D5R) can be attributed to their third intracellular domain and C …
[PDF][PDF] Hideaki Yano1, Davide Provasi2, Ning Sheng Cai1, Marta Filizola2
S Ferré, JA Javitch - 2017 - researchgate.net
Gαs (Gs) and Gαolf (Golf) are highly homologous G protein α subunits that activate
adenylate cyclase, thereby serving as crucial mediators of intracellular signaling. Owing to …
adenylate cyclase, thereby serving as crucial mediators of intracellular signaling. Owing to …