Altered B cell signalling in autoimmunity
DJ Rawlings, G Metzler, M Wray-Dutra… - Nature reviews …, 2017 - nature.com
Recent work has provided new insights into how altered B cell-intrinsic signals—through the
B cell receptor (BCR) and key co-receptors—function together to promote the pathogenesis …
B cell receptor (BCR) and key co-receptors—function together to promote the pathogenesis …
Tonic signals: why do lymphocytes bother?
DR Myers, J Zikherman, JP Roose - Trends in immunology, 2017 - cell.com
Since the 1990s it has been known that B and T lymphocytes exhibit low-level, constitutive
signaling in the basal state (tonic signaling). These lymphocytes display a range of affinity …
signaling in the basal state (tonic signaling). These lymphocytes display a range of affinity …
[PDF][PDF] Analysis of the role of the IL-23/Th17 axis on B cell-mediated autoimmunity
R Pfeifle - 2017 - opus4.kobv.de
Rheumatoid arthritis (RA) is a common autoimmune disease. Early RA is characterized by
an initial break in immunological tolerance, the appearance of specific autoantibodies and a …
an initial break in immunological tolerance, the appearance of specific autoantibodies and a …
The Role of CD1d-Mediated Lipid Presentation by Regulatory B Cells in Invariant Natural Killer T Cell Suppression of Autoimmunity
K Oleinika - 2017 - discovery.ucl.ac.uk
Regulatory B cells (Bregs) express high levels of CD1d that presents lipid antigens to
invariant natural killer T (iNKT) cells. The role of CD1d in Breg biology and the specific …
invariant natural killer T (iNKT) cells. The role of CD1d in Breg biology and the specific …