Long non‐coding RNA s as an epigenetic regulator in human cancers

Y Kondo, K Shinjo, K Katsushima - Cancer science, 2017 - Wiley Online Library
Recent studies have described the important multiple roles of long non‐coding RNA s (lnc
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …

Long non-coding RNAs as biomarkers and therapeutic targets: recent insights into hepatocellular carcinoma

L Qiu, Q Tang, G Li, K Chen - Life sciences, 2017 - Elsevier
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer worldwide, and
the survival rates of patients with HCC remains quite low after 5 years. Long non-coding …

[HTML][HTML] Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Y Niu, F Ma, W Huang, S Fang, M Li, T Wei, L Guo - Molecular cancer, 2017 - Springer
Background Taurine upregulated gene1 (TUG1) as a 7.1-kb lncRNA, has been shown to
play an oncogenic role in various cancers. However, the biological functions of lncRNA …

Long non‐coding RNA TUG 1 promotes migration and invasion by acting as a ce RNA of miR‐335‐5p in osteosarcoma cells

Y Wang, T Yang, Z Zhang, M Lu, W Zhao… - Cancer …, 2017 - Wiley Online Library
Long non‐coding RNA (lnc RNA) have been the focus of increasing attention due to the role
they play in many diseases, including osteosarcoma. The function of taurine upregulated …

[HTML][HTML] Long non-coding RNA TUG1 promotes cervical cancer progression by regulating the miR-138-5p-SIRT1 axis

J Zhu, H Shi, H Liu, X Wang, F Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Increasing evidences showed that long non-coding RNAs (lncRNAs) play vital roles in tumor
progression. Recent studies indicated that lncRNA TUG1 was upregulated and promoted …

LncRNA, TUG1 regulates the oral squamous cell carcinoma progression possibly via interacting with Wnt/β-catenin signaling

S Liang, S Zhang, P Wang, C Yang, C Shang, J Yang… - Gene, 2017 - Elsevier
Oral squamous cell carcinoma (OSCC) is one the most common cancer affecting the head
and neck region, and the molecular mechanisms underlying OSCC development is largely …

[HTML][HTML] Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer

J Ding, M Xie, Y Lian, Y Zhu, P Peng, J Wang, L Wang… - Oncogenesis, 2017 - nature.com
Long noncoding RNAs (lncRNAs) have received increased attention as a new class of
functional regulators involved in human carcinogenesis. HOXA cluster antisense RNA 2 …

New insights into the epigenetics of hepatocellular carcinoma

B Wahid, A Ali, S Rafique… - BioMed Research …, 2017 - Wiley Online Library
Hepatocellular Carcinoma (HCC) is one of the most predominant malignancies with high
fatality rate. This deadly cancer is rising at an alarming rate because it is quite resistant to …

Upregulation of long noncoding RNA TUG1 promotes cervical cancer cell proliferation and migration

Y Hu, X Sun, C Mao, G Guo, S Ye, J Xu, R Zou… - Cancer …, 2017 - Wiley Online Library
Long noncoding RNA s (lnc RNA s), a novel class of transcripts that have critical roles in
carcinogenesis and progression, have emerged as important gene expression modulators …

Long noncoding RNAs in the p53 network

R Chaudhary, A Lal - Wiley Interdisciplinary Reviews: RNA, 2017 - Wiley Online Library
The tumor‐suppressor protein p53 is activated in response to numerous cellular stresses
including DNA damage. p53 functions primarily as a sequence‐specific transcription factor …