Magnetic sensing platform technologies for biomedical applications
Detection and quantification of a variety of micro-and nanoscale entities, eg molecules, cells,
and particles, are crucial components of modern biomedical research, in which biosensing …
and particles, are crucial components of modern biomedical research, in which biosensing …
Splanchnic vein thrombosis in myeloproliferative neoplasms: pathophysiology and molecular mechanisms of disease
J How, A Zhou, ST Oh - Therapeutic advances in …, 2017 - journals.sagepub.com
Myeloproliferative neoplasms (MPNs) are the most common underlying prothrombotic
disorder found in patients with splanchnic vein thrombosis (SVT). Clinical risk factors for …
disorder found in patients with splanchnic vein thrombosis (SVT). Clinical risk factors for …
[HTML][HTML] Ruxolitinib reduces JAK2 p.V617F allele burden in patients with polycythemia vera enrolled in the RESPONSE study
AM Vannucchi, S Verstovsek, P Guglielmelli… - Annals of …, 2017 - Springer
In patients with polycythemia vera (PV), an elevated JAK2 p. V617F allele burden is
associated with indicators of more severe disease (eg, leukocytosis, splenomegaly, and …
associated with indicators of more severe disease (eg, leukocytosis, splenomegaly, and …
The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, double‐blind, double …
R Mesa, AM Vannucchi, A Yacoub… - British journal of …, 2017 - Wiley Online Library
The randomized, double‐blind, double‐dummy, phase 3b RELIEF trial evaluated
polycythaemia vera (PV)‐related symptoms in patients who were well controlled with a …
polycythaemia vera (PV)‐related symptoms in patients who were well controlled with a …
Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms
L Pieri, C Paoli, U Arena, F Marra, F Mori… - American journal of …, 2017 - Wiley Online Library
Splanchnic vein thrombosis (SVT) is one of the vascular complications of myeloproliferative
neoplasms (MPN). We designed a phase 2 clinical trial to evaluate safety and efficacy of …
neoplasms (MPN). We designed a phase 2 clinical trial to evaluate safety and efficacy of …
Benefits and risks of antithrombotic therapy in essential thrombocythemia: a systematic review
Background: Patients with essential thrombocythemia (ET) are at high risk for both
thrombosis and hemorrhage. Purpose: To evaluate the risks and benefits of antithrombotic …
thrombosis and hemorrhage. Purpose: To evaluate the risks and benefits of antithrombotic …
The clonal origins of leukemic progression of myelodysplasia
The genetics behind the progression of myelodysplasia to secondary acute myeloid
leukemia (sAML) is poorly understood. In this study, we profiled somatic mutations and their …
leukemia (sAML) is poorly understood. In this study, we profiled somatic mutations and their …
[HTML][HTML] The role of the extracellular matrix in primary myelofibrosis
O Leiva, SK Ng, S Chitalia, A Balduini, S Matsuura… - Blood cancer …, 2017 - nature.com
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm that arises from clonal
proliferation of hematopoietic stem cells and leads to progressive bone marrow (BM) …
proliferation of hematopoietic stem cells and leads to progressive bone marrow (BM) …
[HTML][HTML] Efficacy of ALK5 inhibition in myelofibrosis
Myelofibrosis (MF) is a bone marrow disorder characterized by clonal myeloproliferation,
aberrant cytokine production, extramedullary hematopoiesis, and bone marrow fibrosis …
aberrant cytokine production, extramedullary hematopoiesis, and bone marrow fibrosis …
[HTML][HTML] Clinical significance of circulating microparticles in Ph-myeloproliferative neoplasms
W Zhang, J Qi, S Zhao, W Shen, L Dai… - Oncology …, 2017 - spandidos-publications.com
Microparticles (MPs) are small membrane vesicles that are classified into subcategories
based on their origin, such as platelet‑derived MPs (PMPs), endothelial MPs (EMPs), red …
based on their origin, such as platelet‑derived MPs (PMPs), endothelial MPs (EMPs), red …