The genomic revolution promises to transform our approach to treat patients by
individualizing treatments, reducing adverse events, and decreasing health care costs. The …

Abstract The Mycobacterium tuberculosis Complex (MTBC) consists of a clonal group of
several mycobacterial lineages pathogenic to a range of different mammalian hosts. In this …

Due to its rapid spread and association with the numerous outbreaks, the global spread of
East Asian lineage of Mycobacterium tuberculosis strains presents a global concern …

Whole-genome sequencing (WGS) has the potential to accelerate drug-susceptibility testing
(DST) to design appropriate regimens for drug-resistant tuberculosis (TB). Several recently …

Tuberculosis (TB) is a contagious disease with a complex epidemiology. Therefore,
molecular typing (genotyping) of Mycobacterium tuberculosis complex (MTBC) strains is of …

Background RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including
regimens with high-dose rifapentine with moxifloxacin. Here, the application of whole …

Despite the efficacy of antibiotics to protect humankind against many deadly pathogens,
such as Mycobacterium tuberculosis, nothing can prevent the emergence of drug-resistant …

Background/objectives: Whole genome sequencing (WGS) has proven to be a powerful
subtyping tool for foodborne pathogenic bacteria like L. monocytogenes. The interests of …

Tuberculosis has plagued mankind over the centuries and probably accompanied modern
Homo sapiens out of Africa. The epidemiological agent of phthisis, also known as …

Mycobacterium tuberculosis is divided into several distinct lineages, and various genetic
markers such as IS-elements, VNTR, and SNPs are used for lineage identification. We …