[HTML][HTML] Epigenetic regulatory mechanisms induced by resveratrol

GFS Fernandes, GDB Silva, AR Pavan, DE Chiba… - Nutrients, 2017 - mdpi.com
Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its
potential therapeutic use in the treatment of many diseases, including cancer, diabetes …

[HTML][HTML] Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways

C Sturm, AE Wagner - International Journal of Molecular Sciences, 2017 - mdpi.com
A high consumption of vegetables belonging to the Brassicaceae family has been related to
a lower incidence of chronic diseases including different kinds of cancer. These beneficial …

[HTML][HTML] EBV based cancer prevention and therapy in nasopharyngeal carcinoma

Y Cao - NPJ precision oncology, 2017 - nature.com
Epstein–Barr virus is an important cancer causing virus. Nasopharyngeal carcinoma is an
infection-related cancer strongly driven by Epstein–Barr virus. In this cancer model, we …

Genetic diversity and evolution of Brassica genetic resources: from morphology to novel genomic technologies–a review

MA El-Esawi - Plant Genetic Resources, 2017 - cambridge.org
Brassica species have an economic and medicinal importance. Estimation of the amount
and distribution of genetic diversity within Brassica species is essential for establishing …

Anticancer natural compounds as epigenetic modulators of gene expression

EA Ratovitski - Current Genomics, 2017 - ingentaconnect.com
Accumulating evidence shows that hallmarks of cancer include:“genetic and epigenetic
alterations leading to inactivation of cancer suppressors, overexpression of oncogenes …

[HTML][HTML] Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A

KS vel Szic, K Declerck, RAJ Crans, J Diddens… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Triple negative breast cancer (TNBC) is characterized by poor prognosis and a DNA
hypomethylation profile. Withaferin A (WA) is a plant derived steroidal lactone which holds …

Epigenetic changes induced by green tea catechins a re associated with prostate cancer

A Giudice, M Montella, M Boccellino… - Current Molecular …, 2017 - ingentaconnect.com
Prostate cancer is one of the most difficult cancers to treat especially when it becomes
hormone resistant such as castrate resistant prostate cancer (CRPC) and subsequent …

Personhood status of the human zygote, embryo, fetus

JJ Miklavcic, P Flaman - The Linacre Quarterly, 2017 - journals.sagepub.com
The fields of biology, medicine, and embryology have described the developmental
milestones of humans throughout gestation in great detail. It is less clear as to when humans …

Epigenetic approach for angiostatic therapy: promising combinations for cancer treatment

RH Berndsen, UK Abdul, A Weiss, M Zoetemelk… - Angiogenesis, 2017 - Springer
Cancer cells are often dependent on epigenetic pathways for their survival. Consequently,
drugs that target the epigenome, rather than the underlying DNA sequence, are currently …

[HTML][HTML] 3, 6-Dihydroxyflavone regulates microRNA-34a through DNA methylation

X Peng, H Chang, J Chen, Q Zhang, X Yu, M Mi - BMC cancer, 2017 - Springer
Background Breast cancer is the common cancer in China. In previous study, we determined
that 3, 6-dihydroxyflavone (3, 6-DHF) increases miR-34a significantly in breast …