[HTML][HTML] Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion
N Bozadjieva, M Blandino-Rosano… - The Journal of …, 2017 - Am Soc Clin Investig
Glucagon plays a major role in the regulation of glucose homeostasis during fed and fasting
states. However, the mechanisms responsible for the regulation of pancreatic α cell mass …
states. However, the mechanisms responsible for the regulation of pancreatic α cell mass …
ADHD, learning difficulties and sleep disturbances associated with KCNJ11‐related neonatal diabetes
Objectives Mutations in KCNJ11 are the most common cause of permanent neonatal
diabetes mellitus (NDM). Approximately 25% of patients have obvious neurological …
diabetes mellitus (NDM). Approximately 25% of patients have obvious neurological …
[HTML][HTML] Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice
E Nuñez-Durán, B Chanclón, S Sütt… - Journal of …, 2017 - joe.bioscientifica.com
Overexpression of bovine growth hormone (bGH) in transgenic (PEPCK-bGH) mice induces
resistance to insulin, which is compensated by a major increase in insulin levels. In these …
resistance to insulin, which is compensated by a major increase in insulin levels. In these …
Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone
AG Yee, PS Freestone, JZ Bai, J Lipski - Experimental Neurology, 2017 - Elsevier
Parkinson's disease (PD) is not only associated with degeneration of dopaminergic
(DAergic) neurons in the Substantia Nigra, but also with profound loss of noradrenergic …
(DAergic) neurons in the Substantia Nigra, but also with profound loss of noradrenergic …
Existence of ATP sensitive potassium currents on human periodontal ligament cells
PTH Tran, YH Lee, JP Bhattarai, SJ Park, HK Yi… - Archives of oral …, 2017 - Elsevier
Objective Potassium channels of the ATP-sensitive family (K ATP channel) are inhibited by
increase in intracellular ATP. Electrophysiological studies have demonstrated that the …
increase in intracellular ATP. Electrophysiological studies have demonstrated that the …
Differential spread of anoxic depolarization contributes to the pattern of neuronal injury after oxygen and glucose deprivation (OGD) in the Substantia Nigra in rat brain …
Anoxic depolarization (AD) is an acute event evoked by brain ischemia, involving a profound
loss of cell membrane potential and swelling that spreads over susceptible parts of the gray …
loss of cell membrane potential and swelling that spreads over susceptible parts of the gray …
The role of selenium in dopamine transmission and modulation by methamphetamine
DJ Torres - 2017 - search.proquest.com
Selenium (Se) is an antioxidant trace element that is important for normal brain function. Se
is incorporated into selenoproteins, a family of proteins with multiple functions that include …
is incorporated into selenoproteins, a family of proteins with multiple functions that include …
Role of glutamate N-Methyl-D-Aspartate receptor surface trafficking in the firing pattern of midbrain dopaminergic neurons
L Etchepare - 2017 - theses.hal.science
Midbrain dopaminergic (DA) neurons play several key functions in the brain such as the
processing of salient information but are also associated with the emergence of pathologies …
processing of salient information but are also associated with the emergence of pathologies …
Appetite Control: Genetic, Immunological and Neurobiological Aspects
C Lindfors - 2017 - search.proquest.com
The overall goal of this thesis is to develop a better understanding of the brain's regulation of
appetite, ie the hypothalamic regulation of hunger and satiety signals. The correct regulation …
appetite, ie the hypothalamic regulation of hunger and satiety signals. The correct regulation …