Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole‐Triazoles as Potential Lanosterol 14α‐Demethylase Inhibitors

NÖ Can, U Acar Çevik, BN Sağlık, S Levent… - Journal of …, 2017 - Wiley Online Library
Due to anticandidal importance of azole compounds, a new series of benzimidazole‐triazole
derivatives (5a–5s) were designed and synthesized as ergosterol inhibitors. The chemical …

[HTML][HTML] Synthesis and anticandidal activity evaluation of new benzimidazole-thiazole derivatives

ZA Kaplancıklı, S Levent, D Osmaniye, BN Sağlık… - Molecules, 2017 - mdpi.com
Azole-based antifungal agents constitute one of the important classes of antifungal drugs.
Hence, in the present work, 12 new benzimidazole-thiazole derivatives 3a–3l were …

[HTML][HTML] Syntheses of Novel 4-Substituted N-(5-amino-1H-1,2,4-triazol-3-yl)pyridine-3-sulfonamide Derivatives with Potential Antifungal Activity

K Szafrański, J Sławiński, A Kędzia, E Kwapisz - Molecules, 2017 - mdpi.com
Candidiasis represent a serious threat for patients with altered immune responses.
Therefore, we have undertaken the synthesis of compounds comprising a pyridine-3 …

[HTML][HTML] Synthesis of oxadiazole-thiadiazole hybrids and their anticandidal activity

S Levent, B Kaya Çavuşoğlu, BN Sağlık, D Osmaniye… - Molecules, 2017 - mdpi.com
In the field of infection management, it is a major challenge to discover a potent and safe
antifungal agent due to the emergence of resistant strains. Hence, the goal of this paper is to …

Л-АЦИЛИМИНОЗАМЕЩЕННЫЕ 2-ОКСА-7-АЗАСПИРО [4.4] НОНА-3, 6, 8-ТРИЕНЫ В СИНТЕЗЕ 3-(Ш-1, 2, 4-ТРИАЗОЛ-3-ИЛ)-3Я-ПИРРОЛ-4-КАРБОНИТРИЛОВ

МЮ Беликов, ИВ Беликова, ОВ Ершов… - Журнал органической …, 2017 - elibrary.ru
При взаимодействии спиросочлененных с фурановым циклом ЗН-пирролов-N-
ацилиминозамещенных 2-окса-7-азаспиро [4.4] нона-3, 6, 8-триенов с …

N-acylimino-substituted 2-oxa-7-azaspiro[4.4]nona-3,6,8-trienes in the synthesis of 3-(1H-1,2,4-triazol-3-yl)-3H-pyrrole-4-carbonitriles

MY Belikov, IV Belikova, OV Ershov… - Russian Journal of …, 2017 - Springer
Reaction with phenylhydrazine of 3 Н-pyrroles spirobound to a furan ring, N-acylimino-
substituted 2-oxa-7-azaspiro [4.4] nona-3, 6, 8-trienes, occurs with a diasteroselective …

Expressão gênica de Candida albicans frente a diferentes concentrações de antifúngicos e antiretrovirais

NC SILVA - 2017 - bdtd.unifal-mg.edu.br
Importantes atributos associados à virulência podem ser observados em Candida spp., tais
como a expressão de genes SAP, os quais são responsáveis por regular a secreção de …