[HTML][HTML] Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

PD Cani, WM de Vos - Frontiers in microbiology, 2017 - frontiersin.org
Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide
epidemic. Among the different environmental factors, the gut microbiota is now considered …

Akkermansia muciniphila and its role in regulating host functions

M Derrien, C Belzer, WM de Vos - Microbial pathogenesis, 2017 - Elsevier
Akkermansia muciniphila is an intestinal bacterium that was isolated a decade ago from a
human fecal sample. Its specialization in mucin degradation makes it a key organism at the …

FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial

K McIntosh, DE Reed, T Schneider, F Dang… - Gut, 2017 - gut.bmj.com
Objective To gain mechanistic insights, we compared effects of low fermentable
oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high …

Intestinal dysbiosis and probiotic applications in autoimmune diseases

GLV de Oliveira, AZ Leite, BS Higuchi… - …, 2017 - Wiley Online Library
In humans, a complex interaction between the host immune system and commensal
microbiota is required to maintain gut homeostasis. In this symbiotic relationship, the …

[HTML][HTML] Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

N Ottman, J Reunanen, M Meijerink, TE Pietilä… - PloS one, 2017 - journals.plos.org
Gut barrier function is key in maintaining a balanced response between the host and its
microbiome. The microbiota can modulate changes in gut barrier as well as metabolic and …

Action and function of Akkermansia muciniphila in microbiome ecology, health and disease

N Ottman, SY Geerlings, S Aalvink, WM de Vos… - Best practice & research …, 2017 - Elsevier
The discovery of Akkermansia muciniphila has opened new avenues for the use of this
abundant intestinal symbiont in next generation therapeutic products, as well as targeting …

[HTML][HTML] Gut metagenomic analysis reveals prominent roles of Lactobacillus and cecal microbiota in chicken feed efficiency

W Yan, C Sun, J Yuan, N Yang - Scientific reports, 2017 - nature.com
Interactions between the host and gut microbiota can affect gut metabolism. In this study, the
individual performances of 252 hens were recorded to evaluate feed efficiency. Hens with …

[HTML][HTML] The gut microbiota of healthy Chilean subjects reveals a high abundance of the phylum Verrucomicrobia

S Fujio-Vejar, Y Vasquez, P Morales, F Magne… - Frontiers in …, 2017 - frontiersin.org
The gut microbiota is currently recognized as an important factor regulating the homeostasis
of the gastrointestinal tract and influencing the energetic metabolism of the host as well as its …

[HTML][HTML] Protective Effect of Akkermansia muciniphila against Immune-Mediated Liver Injury in a Mouse Model

W Wu, L Lv, D Shi, J Ye, D Fang, F Guo, Y Li… - Frontiers in …, 2017 - frontiersin.org
Accumulating evidence indicates that gut microbiota participates in the pathogenesis and
progression of liver diseases. The severity of immune-mediated liver injury is associated …

[HTML][HTML] Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity

P Mehrpouya-Bahrami, KN Chitrala, MS Ganewatta… - Scientific reports, 2017 - nature.com
Obesity is characterized by chronic low-grade, systemic inflammation, altered gut microbiota,
and gut barrier disruption. Additionally, obesity is associated with increased activity of …