Enrichment and single-cell analysis of circulating tumor cells

Y Song, T Tian, Y Shi, W Liu, Y Zou, T Khajvand… - Chemical …, 2017 - pubs.rsc.org
Up to 90% of cancer-related deaths are caused by metastatic cancer. Circulating tumor cells
(CTCs), a type of cancer cell that spreads through the blood after detaching from a solid …

Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration

S Pacelli, S Basu, J Whitlow, A Chakravarti… - Advanced drug delivery …, 2017 - Elsevier
A leading strategy in tissue engineering is the design of biomimetic scaffolds that stimulate
the body's repair mechanisms through the recruitment of endogenous stem cells to sites of …

Aptamer/AuNP biosensor for colorimetric profiling of exosomal proteins

Y Jiang, M Shi, Y Liu, S Wan, C Cui… - Angewandte Chemie …, 2017 - Wiley Online Library
Exosomes constitute an emerging biomarker for cancer diagnosis because they carry
multiple proteins that reflect the origins of parent cells. Assessing exosome surface proteins …

Enhanced isolation and release of circulating tumor cells using nanoparticle binding and ligand exchange in a microfluidic chip

MH Park, E Reátegui, W Li, SN Tessier… - Journal of the …, 2017 - ACS Publications
The detection of rare circulating tumor cells (CTCs) in the blood of cancer patients has the
potential to be a powerful and noninvasive method for examining metastasis, evaluating …

DNA hydrogel with aptamer-toehold-based recognition, cloaking, and decloaking of circulating tumor cells for live cell analysis

P Song, D Ye, X Zuo, J Li, J Wang, H Liu, MT Hwang… - Nano …, 2017 - ACS Publications
Circulating tumor cells (CTCs) contain molecular information on the primary tumor and can
be used for predictive cancer diagnostics. Capturing rare live CTCs and their quantification …

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

M Poudineh, PM Aldridge, S Ahmed, BJ Green… - Nature …, 2017 - nature.com
Profiling the heterogeneous phenotypes of rare circulating tumour cells (CTCs) in whole
blood is critical to unravelling the complex and dynamic properties of these potential clinical …

Reversible control of cell membrane receptor function using DNA nano-spring multivalent ligands

K Zhang, R Deng, Y Sun, L Zhang, J Li - Chemical science, 2017 - pubs.rsc.org
Chemically functionalized and nanostructured materials, which mimic the features of the
natural extracellular matrix, provide a tool to organize cell surface receptors into nanoscale …

Aptamer-functionalized nano/micro-materials for clinical diagnosis: isolation, release and bioanalysis of circulating tumor cells

Y Zhao, D Xu, W Tan - Integrative Biology, 2017 - academic.oup.com
Detection of rare circulating tumor cells (CTCs) in peripheral blood is a challenging, but
necessary, task in order to diagnose early onset of metastatic cancer and to monitor …

Isolation of circulating plasma cells in multiple myeloma using CD138 antibody-based capture in a microfluidic device

MA Qasaimeh, YC Wu, S Bose, A Menachery… - Scientific reports, 2017 - nature.com
The necessity for bone marrow aspiration and the lack of highly sensitive assays to detect
residual disease present challenges for effective management of multiple myeloma (MM), a …

Efficient capture of cancer cells by their replicated surfaces reveals multiscale topographic interactions coupled with molecular recognition

W Wang, H Cui, P Zhang, J Meng… - ACS Applied Materials …, 2017 - ACS Publications
Cell–surface topographic interactions can direct the design of biointerfaces, which have
been widely used in isolation of circulating tumor cells or fundamental cell biological …