Fine‐tuning PERK signaling for neuroprotection

M Halliday, D Hughes, GR Mallucci - Journal of neurochemistry, 2017 - Wiley Online Library
Protein translation and folding are tightly controlled processes in all cells, by proteostasis, an
important component of which is the unfolded protein response (UPR). During periods of …

[HTML][HTML] Lipid-induced endoplasmic reticulum stress in X-linked adrenoleukodystrophy

MC van de Beek, R Ofman, I Dijkstra, F Wijburg… - … et Biophysica Acta (BBA …, 2017 - Elsevier
X-linked adrenoleukodystrophy (ALD) is a progressive neurodegenerative disease that is
caused by mutations in the ABCD1 gene and characterized by elevated levels of very long …

An oasis in the desert of cancer chemotherapeutic resistance: The enlightenment from reciprocal crosstalk between signaling pathways of UPR and autophagy in …

Y Zhang, X Qu, L Jiang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Endoplasmic reticulum (ER), principal but complex, functions as the pleiotropic organelle for
proper protein folding, Ca 2+ storage as well as lipid and carbohydrate metabolisms …

Genetic deficiency in neuronal peroxisomal fatty acid β-oxidation causes the interruption of dauer development in Caenorhabditis elegans

S Park, YK Paik - Scientific reports, 2017 - nature.com
Although peroxisomal fatty acid (FA) β-oxidation is known to be critical for animal
development, the cellular mechanisms that control the manner in which its neuronal …

[引用][C] BBA-Molecular Basis of Disease

MC van de Beek, R Ofman, I Dijkstra, F Wijburg…