Beyond liposomes: Recent advances on lipid based nanostructures for poorly soluble/poorly permeable drug delivery
Solid lipid nanoparticle (SLN), nanostructured lipid carriers (NLC) and hybrid nanoparticles,
have gained increasing interest as drug delivery systems because of their potential to load …
have gained increasing interest as drug delivery systems because of their potential to load …
In vitro release kinetics of microencapsulated materials and the effect of the food matrix
Many biomaterials are encapsulated to preserve their health-promoting properties and
promote targeted delivery. Numerous papers have been published about extraction and …
promote targeted delivery. Numerous papers have been published about extraction and …
Enhanced Solubility and Bioavailability of Naringenin via Liposomal Nanoformulation: Preparation and In Vitro and In Vivo Evaluations
Y Wang, S Wang, CK Firempong, H Zhang, M Wang… - Aaps pharmscitech, 2017 - Springer
This study was aimed at preparing orally administered naringenin-loaded liposome for
pharmacokinetic and tissue distribution studies in animal models. The liposomal system …
pharmacokinetic and tissue distribution studies in animal models. The liposomal system …
Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation
N Dudhipala, K Veerabrahma - European Journal of Pharmaceutics and …, 2017 - Elsevier
The intent of this investigation was to improve pharmacokinetic (PK) and pharmacodynamic
(PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs). RC is anti …
(PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs). RC is anti …
Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling
A Ruff, T Fiolka, ES Kostewicz - European Journal of Pharmaceutical …, 2017 - Elsevier
The aim of this study was to optimize the in vitro transfer model and to increase its
biorelevance to more accurately mimic the in vivo supersaturation and precipitation …
biorelevance to more accurately mimic the in vivo supersaturation and precipitation …
Enhanced oral bioavailability of valsartan using a polymer-based supersaturable self-microemulsifying drug delivery system
DW Yeom, BR Chae, HY Son, JH Kim… - International Journal …, 2017 - Taylor & Francis
A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was
successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a …
successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a …
The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system …
Y Tsume, K Matsui, AL Searls, S Takeuchi… - European Journal of …, 2017 - Elsevier
The development of formulations and the assessment of oral drug absorption for
Biopharmaceutical Classification System (BCS) class IIb drugs is often a difficult issue due to …
Biopharmaceutical Classification System (BCS) class IIb drugs is often a difficult issue due to …
Fabrication, characterization and in vitro evaluation of silibinin nanoparticles: an attempt to enhance its oral bioavailability
MUK Sahibzada, A Sadiq, S Khan… - Drug Design …, 2017 - Taylor & Francis
Background Silibinin has gained in importance in the past few decades as a hepatoprotector
and is used widely as oral therapy for toxic liver damage, liver cirrhosis, and chronic …
and is used widely as oral therapy for toxic liver damage, liver cirrhosis, and chronic …
Nanoparticulate fingolimod delivery system based on biodegradable poly (3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV): design, optimization, characterization and …
L Rezaie Shirmard, N Bahari Javan… - Pharmaceutical …, 2017 - Taylor & Francis
This study was focused on the fabrication, statistical optimization and in vitro
characterization of poly (hydroxybutyrate-co-hydroxyvalerate)(PHBV) nanoparticles loaded …
characterization of poly (hydroxybutyrate-co-hydroxyvalerate)(PHBV) nanoparticles loaded …
Metabolic pathways and pharmacokinetics of natural medicines with low permeability
M Zeng, L Yang, D He, Y Li, M Shi… - Drug metabolism …, 2017 - Taylor & Francis
Drug metabolism plays an important role in the drug disposal process. Differences in
pharmacokinetics among individuals are the basis for personalized medicine. Natural …
pharmacokinetics among individuals are the basis for personalized medicine. Natural …