The GMZ2 malaria vaccine: from concept to efficacy in humans
Introduction: GMZ2 is a recombinant protein consisting of conserved domains of GLURP and
MSP3, two asexual blood-stage antigens of Plasmodium falciparum, and is designed with …
MSP3, two asexual blood-stage antigens of Plasmodium falciparum, and is designed with …
Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the …
Background Plasmodium falciparum genetic diversity and multiplicity of infection (MOI) are
parasite features that have been suggested to influence the acquisition of protective …
parasite features that have been suggested to influence the acquisition of protective …
Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium …
Vaccination is the most effective prophylactic tool against infectious diseases. Despite
continued efforts to control malaria, the disease still generally represents a significant unmet …
continued efforts to control malaria, the disease still generally represents a significant unmet …
Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites: Naturally Acquired Humoral Immune Response and B-Cell Epitope Mapping in Brazilian …
RN Rodrigues-da-Silva, IF Soares… - Frontiers in …, 2017 - frontiersin.org
The cell-traversal protein for ookinetes and sporozoites (CelTOS), a highly conserved
antigen involved in sporozoite motility, plays an important role in the traversal of host cells …
antigen involved in sporozoite motility, plays an important role in the traversal of host cells …
Antibody responses to P. falciparum blood stage antigens and incidence of clinical malaria in children living in endemic area in Burkina Faso
MK Cherif, O Ouédraogo, GS Sanou, A Diarra… - BMC research …, 2017 - Springer
Background High parasite-specific antibody levels are generally associated with low
susceptibility to Plasmodium falciparum malaria. This has been supported by several studies …
susceptibility to Plasmodium falciparum malaria. This has been supported by several studies …
Assessment of the Combined Effect of Epstein–Barr Virus and Plasmodium falciparum Infections on Endemic Burkitt Lymphoma Using a Multiplex Serological …
R Aguilar, D Casabonne… - Frontiers in …, 2017 - frontiersin.org
Epstein–Barr virus (EBV) is a necessary cause of endemic Burkitt lymphoma (eBL), while the
role of Plasmodium falciparum in eBL remains uncertain. This study aimed to generate new …
role of Plasmodium falciparum in eBL remains uncertain. This study aimed to generate new …
Naturally acquired immune responses to thrombospondin-related adhesion protein (TRAP) of Plasmodium vivax in patients from areas of unstable malaria …
S Nazeri, S Zakeri, AA Mehrizi, ND Djadid - Acta tropica, 2017 - Elsevier
A key tool for the control, elimination, and eradication of Plasmodium vivax is the
development of an effective vaccine. The thrombospondin-related adhesion protein (TRAP) …
development of an effective vaccine. The thrombospondin-related adhesion protein (TRAP) …
Expression, purification and characterization of GMZ2'. 10C, a complex disulphide-bonded fusion protein vaccine candidate against the asexual and sexual life-stages …
UH Mistarz, SK Singh, TTTN Nguyen, W Roeffen… - Pharmaceutical …, 2017 - Springer
Purpose Production and characterization of a chimeric fusion protein (GMZ2'. 10C) which
combines epitopes of key malaria parasite antigens: glutamate-rich protein (GLURP) …
combines epitopes of key malaria parasite antigens: glutamate-rich protein (GLURP) …
[HTML][HTML] Synthetic antigens derived from Plasmodium falciparum sporozoite, liver, and blood stages: Naturally acquired immune response and human leukocyte …
LR Pratt-Riccio, DDS Perce-Da-Silva… - The American Journal …, 2017 - ncbi.nlm.nih.gov
Peptide vaccine strategies using Plasmodium-derived antigens have emerged as an
attractive approach against malaria. However, relatively few studies have been conducted …
attractive approach against malaria. However, relatively few studies have been conducted …
Control of malaria by bio-therapeutics and drug delivery systems
MM Al Qaraghuli, MA Obeid… - Journal of Medical …, 2017 - strathprints.strath.ac.uk
Malaria is an ubiquitous disease that can affect more than 40% of the world's population
who live with some risk of contracting this disease. The World Health Organization (WHO) …
who live with some risk of contracting this disease. The World Health Organization (WHO) …