Ambient mass spectrometry in cancer research
Ambient ionization mass spectrometry was developed as a sample preparation-free
alternative to traditional MS-based workflows. Desorption electrospray ionization (DESI)-MS …
alternative to traditional MS-based workflows. Desorption electrospray ionization (DESI)-MS …
Mass spectrometry imaging in oncology drug discovery
RJA Goodwin, J Bunch, DF McGinnity - Advances in cancer research, 2017 - Elsevier
Over the last decade mass spectrometry imaging (MSI) has been integrated in to many
areas of drug discovery and development. It can have significant impact in oncology drug …
areas of drug discovery and development. It can have significant impact in oncology drug …
Faster, more reproducible DESI-MS for biological tissue imaging
A new, more robust sprayer for desorption electrospray ionization (DESI) mass spectrometry
imaging is presented. The main source of variability in DESI is thought to be the uncontrolled …
imaging is presented. The main source of variability in DESI is thought to be the uncontrolled …
Mass spectrometry imaging of kidney tissue sections of rat subjected to unilateral ureteral obstruction
H Liu, W Li, Q He, J Xue, J Wang, C Xiong, X Pu… - Scientific reports, 2017 - nature.com
Chronic kidney disease (CKD) poses a serious threat to the quality of human life and health
with an increasing incidence worldwide. Renal fibrosis is closely related to CKD and …
with an increasing incidence worldwide. Renal fibrosis is closely related to CKD and …
Raster-mode continuous-flow liquid microjunction mass spectrometry imaging of proteins in thin tissue sections
Mass spectrometry imaging by use of continuous-flow liquid microjunction sampling at
discrete locations (array mode) has previously been demonstrated. In this Letter, we …
discrete locations (array mode) has previously been demonstrated. In this Letter, we …
In situ hydrogel conditioning of tissue samples to enhance the drug's sensitivity in ambient mass spectrometry imaging
X Song, Z Luo, X Li, T Li, Z Wang, C Sun… - Analytical …, 2017 - ACS Publications
Ion suppression from the tissue matrix has a severe effect on the mass spectrometry imaging
(MSI) of drugs. This problem hinders further applications of MSI in preclinical drug research …
(MSI) of drugs. This problem hinders further applications of MSI in preclinical drug research …
[HTML][HTML] Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD
MJ Lyall, J Cartier, JA Richards, D Cobice… - Wellcome open …, 2017 - ncbi.nlm.nih.gov
Background: Non-alcoholic fatty liver disease (NAFLD) is a global health issue. Dietary
methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis (NASH) …
methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis (NASH) …
Quantitative mass spectrometry imaging of molecules in biological systems
I Lanekoff, J Laskin - Advances in chromatography, 2017 - taylorfrancis.com
In quantitative mass spectrometry imaging (Q-MSI) experiments, one or more standards are
either deposited directly onto the sample or delivered to the sample via the extraction …
either deposited directly onto the sample or delivered to the sample via the extraction …
MALDI-MS of drugs: Profiling, imaging, and steps towards quantitative analysis
SD Turker, WB Dunn, J Wilkie - Applied Spectroscopy Reviews, 2017 - Taylor & Francis
Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique which can
be used in mass spectrometry to produce ions from biomolecules without inducing the …
be used in mass spectrometry to produce ions from biomolecules without inducing the …
[PDF][PDF] Methyl donor deficient diets cause distinct alterations in lipid
MJ Lyall, J Cartier, JA Richards, D Cobice, JP Thomson… - 2017 - academia.edu
Non-alcoholic fatty liver disease (NAFLD) is the predominant cause of chronic liver disease
in the developed world, with an estimated prevalence of between 20–68% 1. The …
in the developed world, with an estimated prevalence of between 20–68% 1. The …