Tumor-associated macrophages (TAM) have served as a paradigm of cancer-related
inflammation. Moreover, investigations on TAM have led to the dissection of macrophage …

Necrotizing enterocolitis (NEC) is the most common life threatening condition affecting
preterm infants. NEC occurs in 1–5% of all neonatal intensive care admissions and 5–10 …

Stroke is one of the leading causes of morbidity and mortality worldwide. Inflammation,
oxidative stress, apoptosis, and excitotoxicity contribute to neuronal death during ischemic …

Acemannan, an acetylated polymannose from Aloe vera, has immunomodulatory effects. We
investigated whether acemannan induces IL-6 and-8 expression and NF-κB/DNA binding in …

The Toll‐like receptor (TLR) adaptor proteins myeloid differentiating factor 88 (MyD88) and
Toll, interleukin‐1 receptor and resistance protein (TIR) domain‐containing adaptor inducing …

To determine the mechanism underlying the anti-inflammatory effects of plant sphingolipids,
especially plant glucosylceramide (GlcCer), the effects of plant sphingolipids on …

Chemotherapeutics are often used to inhibit the proliferation of cancer cells. However, they
can also harm healthy cells and cause side effects such as immunosuppression. Especially …

The biological function of interleukin‐10 (IL‐10) and the relationship between IL‐10
secretion and the Toll‐like receptor 2 (TLR 2) expression levels in the central nervous …

Phlorizin is a member of the chalcone class of organic compounds that was originally
extracted from apples. The aim of the study was to investigate the attenuation effect of …

Durante las últimas décadas se han comenzado a desarrollar las denominadas “vacunas
de la nueva generación”. Su diseño difiere de las vacunas tradicionales y está basado en el …