Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

Cryptococcus neoformans is an encapsulated fungal pathogen that causes cryptococcosis,
which is a major opportunistic infection in immunosuppressed individuals. Mammalian β …

Cryptococcus neoformans is an environmental fungus that can cause lethal
meningoencephalitis in immunocompromised individuals. The mechanisms by which …

The effectiveness of macrophages in the response to systemic candidiasis is crucial to an
effective clearance of the pathogen. The secretion of proteins, mRNAs, noncoding RNAs …

Cryptococcus neoformans is an environmental encapsulated yeast that behaves as an
opportunistic pathogen in immunocompromised individuals. The capsule is the main …

Infectious diseases are the leading cause of death of children worldwide, causing a
tenacious and major public-health burden. The dynamic interplay between pathogens and …

The pathogenic fungus Cryptococcus neoformans delivers virulence factors such as capsule
polysaccharide to the cell surface to cause disease in vertebrate hosts. In this study, we …

Sphingolipids (SPLs) are key components of the plasma membrane in yeast and
filamentous fungi. These molecules are involved in a number of cellular processes, and …

Pathogenic cryptococci are encapsulated yeast that can cause severe meningoencephalitis.
Existing therapeutic options are dated and there is a growing need for new alternative …