Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics
MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …
Impact of adalimumab treatment on cardiovascular risk biomarkers in psoriasis: results of a pilot study
S Gkalpakiotis, M Arenbergerova… - The Journal of …, 2017 - Wiley Online Library
Psoriasis is a chronic systemic immune‐mediated inflammatory dermatosis associated with
several comorbidities. Psoriasis patients are at increased risk of developing cardiovascular …
several comorbidities. Psoriasis patients are at increased risk of developing cardiovascular …
In vivo distribution of single chain variable fragment (scFv) against atherothrombotic oxidized LDL/β2-glycoprotein I complexes into atherosclerotic plaques of WHHL …
T Sasaki, K Kobayashi, S Kita, K Kojima, H Hirano… - Autoimmunity …, 2017 - Elsevier
Abstract Background Oxidized LDL (oxLDL) can exist as a complex with β 2-glycoprotein I (β
2 GPI) in plasma/serum of patients with non-autoimmune atherosclerotic disease or …
2 GPI) in plasma/serum of patients with non-autoimmune atherosclerotic disease or …
The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in …
J Li, C Yu, R Wang, J Xu, Y Chi, J Qin, Q Liu - The International Journal of …, 2017 - Elsevier
CD36 signal transduction modulates the uptake of oxidized low-density lipoprotein (oxLDL)
and foam cell formation. We previously observed that 7-ketocholesteryl-9-carboxynonanoate …
and foam cell formation. We previously observed that 7-ketocholesteryl-9-carboxynonanoate …
Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages
N Domingues, LMBB Estronca, J Silva… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Rationale Cholesteryl hemiesters are oxidation products of polyunsaturated fatty acid esters
of cholesterol. Their oxo-ester precursors have been identified as important components of …
of cholesterol. Their oxo-ester precursors have been identified as important components of …
The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ
J Li, Z Xiu, R Wang, C Yu, Y Chi, J Qin, C Fu… - Life Sciences, 2017 - Elsevier
Aim Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), a specific membrane
receptor for oxidized low-density lipoprotein (oxLDL), plays a crucial role in atherosclerosis …
receptor for oxidized low-density lipoprotein (oxLDL), plays a crucial role in atherosclerosis …
[HTML][HTML] 血浆糖蛋白β2-GPI分子结构域与ox-LDL结合机制
张鹤， 李敬达， 陈阿梅， 刘庆平 - 生物工程学报, 2017 - cjb.ijournals.cn
通过酵母重组P. rβ 2-GPI-DV (β 2 糖蛋白I 第5 结构域) 蛋白的荧光, 圆二色谱及分子对接模拟,
分析血浆糖蛋白β 2-GPI-DV 分子结构域与ox-LDL 的结合机制. SDS-PAGE, Western blotting …
分析血浆糖蛋白β 2-GPI-DV 分子结构域与ox-LDL 的结合机制. SDS-PAGE, Western blotting …
Inflammasomes and Inflammatory Cytokines in Early Atherosclerosis
Chronic dysregulation of early proatherogenic inflammatory pathways may lead to the
activation of innate and adaptive immune responses that affect the endothelium, platelets …
activation of innate and adaptive immune responses that affect the endothelium, platelets …