For the first time in decades, patients with difficult-to-treat cancers such as advanced stage
metastatic melanoma are being offered a glimpse of hope in the form of immunotherapies …

Upon antigen stimulation, quiescent naive T cells undergo a phase of cell mass
accumulation followed by cell cycle entry, clonal expansion, differentiation into functional …

Significance: Myocardial ischemia/reperfusion (I/R) is an important complication of
reperfusion therapy for myocardial infarction (MI). It is a complex process involving metabolic …

Methicillin-resistant Staphylococcus aureus (MRSA) is the major pathogen causing serious
hospital infections worldwide. With the emergence and rapid spread of drug-resistant …

The interaction between the nervous and immune systems during aging is an area of avid
interest, but many aspects remain unclear. This is due, not only to the complexity of the …

The activation of cell-mediated and humoral immune responses to Mycobacterium
tuberculosis (Mtb) is critical for protection against the pathogen and nanoparticle-mediated …

Zearalenone (ZEA) is a non-steroidal estrogenic mycotoxin produced by Fusarium species.
The toxicity of ZEA has been evaluated for reproductive and developmental effects; …

The interaction between T cells and the central nervous system (CNS) in homeostasis and
injury has been recognized being both pathogenic (CD4+ T-helper 1-Th1, Th17 and γδT) …

Memory CD8 T cells can be activated and induced to produce cytokines and increase stores
of cytolytic proteins not only in response to cognate antigen (Ag) but also in response to …

CD8 T cells are key components of the immune response to viruses, but their roles in the
pathogenesis of adenovirus respiratory infection have not been characterized. We used …