[HTML][HTML] A novel platform for immune tolerance induction in hemophilia A mice

S Merlin, ES Cannizzo, E Borroni, V Bruscaggin… - Molecular Therapy, 2017 - cell.com
Hemophilia A (HA) is an X-linked bleeding disease caused by factor VIII (FVIII) deficiency.
We previously demonstrated that FVIII is produced specifically in liver sinusoid endothelial …

[HTML][HTML] R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature

F Li, J Sawada, M Komatsu - Nature communications, 2017 - nature.com
The formation of endothelial lumen is fundamental to angiogenesis and essential to the
oxygenation of hypoxic tissues. The molecular mechanism underlying this important process …

[PDF][PDF] Lentiviral Magnetic Microbubbles: A guidable tool enabling targeted gene transfer to vascular endothelium in vivo

Y Heun - 2017 - edoc.ub.uni-muenchen.de
By definition, gene therapy is the delivery of recombinant nucleic acids to somatic host cells
with the intention to modulate endogenous gene expression thereby achieving significant …

[HTML][HTML] Investigation of human embryonic stem cell differentiation towards endothelial lineages

V Stelmanis - 2017 - theses.gla.ac.uk
Cardiovascular disease represents a significant socio-economic burden and minimally
invasive therapies that address the needs of patients suffering with peripheral arterial …