Transport of drugs from blood vessels to tumour tissue
MW Dewhirst, TW Secomb - Nature Reviews Cancer, 2017 - nature.com
The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …
To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes
Thermosensitive liposomes have been put forward as a strategy to improve upon the limited
tumor drug availability associated with conventional non-thermosensitive liposomes …
tumor drug availability associated with conventional non-thermosensitive liposomes …
[HTML][HTML] Focused ultrasound hyperthermia mediated drug delivery using thermosensitive liposomes and visualized with in vivo two-photon microscopy
The future of nanomedicines in oncology requires leveraging more than just the passive
drug accumulation in tumors through the enhanced permeability and retention effect …
drug accumulation in tumors through the enhanced permeability and retention effect …
Highlights in nanocarriers for the treatment against cervical cancer
KP Medina-Alarcón, AR Voltan… - Materials Science and …, 2017 - Elsevier
Cervical cancer is the second most common malignant tumor in women worldwide and has
a high mortality rate, especially when it is associated with human papillomavirus (HPV). In …
a high mortality rate, especially when it is associated with human papillomavirus (HPV). In …
Possible role of nanocarriers in drug delivery against cervical cancer
Introduction: Cervical cancer is the second most common cancer and the largest cancer
killer among women in most developing countries including India. Although, various drugs …
killer among women in most developing countries including India. Although, various drugs …
Significant radiation enhancement effects by gold nanoparticles in combination with cisplatin in triple negative breast cancer cells and tumor xenografts
L Cui, S Her, M Dunne, GR Borst… - Radiation …, 2017 - meridian.allenpress.com
Gold nanoparticles (AuNPs) and cisplatin have been explored in concomitant
chemoradiotherapy, wherein they elicit their effects by distinct and overlapping mechanisms …
chemoradiotherapy, wherein they elicit their effects by distinct and overlapping mechanisms …
[HTML][HTML] State of the art of stimuli-responsive liposomes for cancer therapy
E Heidarli, S Dadashzadeh, A Haeri - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target
site are the most clinically important and challenging goals in cancer therapy. Liposomes …
site are the most clinically important and challenging goals in cancer therapy. Liposomes …
Thermosensitive nanomedicines could revolutionize thermal therapy in oncology
Technologies that enable thermal therapy treatments are now clinically viable and most
ongoing hyperthermia clinical trials in oncology incorporate chemotherapy. Given the …
ongoing hyperthermia clinical trials in oncology incorporate chemotherapy. Given the …
Therapeutic efficacy of cisplatin thermosensitive liposomes upon mild hyperthermia in C26 tumor bearing BALB/c mice
This study reports on the activity of thermosensitive liposomes (TSLs) incorporating different
HSPC ratios in DPPC/MSPC/PEG2000-DSPE matrix (90/10/4) plus mild hyperthermia …
HSPC ratios in DPPC/MSPC/PEG2000-DSPE matrix (90/10/4) plus mild hyperthermia …
Tumor microenvironment determines response to a heat-activated thermosensitive liposome formulation of cisplatin in cervical carcinoma
Significant heterogeneity in the tumor microenvironment of human cervical cancer patients is
known to challenge treatment outcomes in this population. The current standard of care for …
known to challenge treatment outcomes in this population. The current standard of care for …