In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
Abstract The human ClC-Kb channel plays a key role in exporting chloride ions from the
cytosol and is known to be involved in Bartter syndrome type 3 when its permeation capacity …
cytosol and is known to be involved in Bartter syndrome type 3 when its permeation capacity …
Pharmacovigilance database search discloses ClC‐K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan
P Imbrici, D Tricarico, GF Mangiatordi… - British journal of …, 2017 - Wiley Online Library
Abstract Background and Purpose Human ClC‐K chloride channels are highly attractive
targets for drug discovery as they have a variety of important physiological functions and are …
targets for drug discovery as they have a variety of important physiological functions and are …
Regulation of Calcium in Muscle Physiology
S Rajagopal, M Ponnusamy, S Rajagopal… - Calcium Signaling: From …, 2017 - Springer
The physiological and biochemical roles of cells are controlled by calcium ions. Calcium
acts as a second messenger in signal transduction pathways, in neurotransmitter release …
acts as a second messenger in signal transduction pathways, in neurotransmitter release …
Transcriptional Regulation and Epigenetics of Pendrin
J Rozenfeld, C Nofziger, O Kladnitsky, SL Alper… - The Role of Pendrin in …, 2017 - Springer
The SLC26A4 gene's 21 exons on chromosome 7q31. 1 encode the pendrin (SLC26A4)
Cl−/anion exchanger. SLC26A4 is highly expressed in the epithelial cells of kidney, thyroid …
Cl−/anion exchanger. SLC26A4 is highly expressed in the epithelial cells of kidney, thyroid …
[引用][C] Outcome of a public consultation on the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values …
European Food Safety Authority (EFSA) - 2017