Efficacy of platelet-rich plasma in the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials

WL Dai, AG Zhou, H Zhang, J Zhang - Arthroscopy: The Journal of …, 2017 - Elsevier
Purpose To use meta-analysis techniques to evaluate the efficacy and safety of platelet-rich
plasma (PRP) injections for the treatment knee of osteoarthritis (OA). Methods We performed …

What drives osteoarthritis?—synovial versus subchondral bone pathology

T Hügle, J Geurts - Rheumatology, 2017 - academic.oup.com
Subchondral bone and the synovium play an important role in the initiation and progression
of OA. MRI often permits an early detection of synovial hypertrophy and bone marrow …

Characterization of the proinflammatory profile of synovial fluid‐derived exosomes of patients with osteoarthritis

R Domenis, R Zanutel, F Caponnetto… - Mediators of …, 2017 - Wiley Online Library
The purpose of this study is to characterize synovial fluid‐(SF‐) derived exosomes of
patients with gonarthrosis comparing two methods of isolation and to investigate their …

Nanoindentation modulus of murine cartilage: a sensitive indicator of the initiation and progression of post-traumatic osteoarthritis

B Doyran, W Tong, Q Li, H Jia, X Zhang, C Chen… - Osteoarthritis and …, 2017 - Elsevier
Objective This study aims to demonstrate that cartilage nanoindentation modulus is a highly
sensitive indicator of the onset and spatiotemporal progression of post-traumatic …

Developing anti-inflammatory therapeutics for patients with osteoarthritis

AM Philp, ET Davis, SW Jones - Rheumatology, 2017 - academic.oup.com
OA is the most common joint disorder in the world, but there are no approved therapeutics to
prevent disease progression. Historically, OA has been considered a wear-and-tear joint …

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis

A Larrañaga-Vera, A Lamuedra, S Pérez-Baos… - Arthritis research & …, 2017 - Springer
Abstract Background Metabolic syndrome (MetS) may be associated with knee osteoarthritis
(OA), but the association between the individual components and OA are not well …

Молекулярные эффекты хондрогарда при остеоартрите и грыжах межпозвоночного диска

АМ Лила, ОА Громова, ИЮ Торшин… - Неврология …, 2017 - cyberleninka.ru
Хондроитина сульфаты (ХС) являются «строительным материалом» хряща,
оказывают противовоспалительный и антиоксидантный эффект. Приведены …

[HTML][HTML] Concentrations of synovial fluid biomarkers and the prediction of knee osteoarthritis 16 years after anterior cruciate ligament injury

P Neuman, LE Dahlberg, M Englund… - Osteoarthritis and …, 2017 - Elsevier
Objective To describe the longitudinal patterns of release, and investigate the association
between a set of synovial fluid biomarkers at the acute and chronic stage and the …

Molecular effects of chondroguard in osteoarthritis and herniated discs

AM Lila, OA Gromova, IY Torshin… - Neurology …, 2017 - nnp.ima-press.net
Chondroitin sulfates (CS) are a building material for the cartilage and have anti-inflammatory
and antioxidant effects. The paper gives the results of analyzing the pharmaceutical …

S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis

NAJ Cremers, MHJ van den Bosch, S van Dalen… - Arthritis research & …, 2017 - Springer
Background Monocytes are dominant cells present within the inflamed synovium during
osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro …