Th1 and Th17 cells have an established role in protective immunity to Bordetella pertussis,
but this evidence is based largely on peripheral T cells. There is emerging evidence that …

Despite high pertussis vaccine coverage, reported cases of whooping cough (pertussis)
have increased over the last decade in the United States and other developed countries …

Pertussis, or whooping cough, caused by the obligate human pathogen Bordetella pertussis
is undergoing a worldwide resurgence. The majority of studies of this pathogen are …

Whooping cough, or pertussis, is a contagious disease of the respiratory tract that is re-
emerging worldwide despite high vaccination coverage. The causative agent of this disease …

This module is part of the WHO series The Immunological Basis for Immunization, which was
initially developed in 1993 as a set of eight modules, comprising one module on general …

Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide.
In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014–2016 …

Pertussis epidemics have displayed substantial spatial heterogeneity in countries with high
socioeconomic conditions and high vaccine coverage. This study aims to investigate the …

Vaccines against pertussis have been available for more than 60 years. Nonetheless, this
highly contagious disease is reemerging even in countries with high vaccination coverage …

We evaluated a commercial loop-mediated isothermal amplification (LAMP) assay kit for
Bordetella pertussis detection. The LAMP primers were designed to target the ptxP1 allele of …

Bordetella pertussis causes whooping cough, a severe and prolonged respiratory disease
that results inhas high morbidity and mortality rates, particularly in developing countries. The …