Genetic insights into the neurodevelopmental origins of schizophrenia
R Birnbaum, DR Weinberger - Nature Reviews Neuroscience, 2017 - nature.com
Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …
neurobiological investigation. Although the underlying causal mechanisms remain …
Systems biology in the central nervous system: a brief perspective on essential recent advancements
As recent advances in human genetics have begun to more rapidly identify the individual
genes contributing to risk of psychiatric disease, the spotlight now turns to understanding …
genes contributing to risk of psychiatric disease, the spotlight now turns to understanding …
Developmental and genetic regulation of the human cortex transcriptome in schizophrenia
GWAS have identified over 108 loci that confer risk for schizophrenia, but risk mechanisms
for individual loci are largely unknown. Using developmental, genetic, and illness-based …
for individual loci are largely unknown. Using developmental, genetic, and illness-based …
Sciences de l'information pour l'étude des systèmes biologiques (exemple du vieillissement du système immunitaire)
W Bedhiafi - 2017 - theses.hal.science
Le laboratoire i3 et le laboratoire LGIPH, utilisent des approches à haut débit pour l'étude du
système immunitaire et ces disfonctionnements. Des limites ont été observées quant à …
système immunitaire et ces disfonctionnements. Des limites ont été observées quant à …
DLPFC Transcriptome Defines Two Molecular Subtypes of Schizophrenia
C Harker Rhodes, EFW Bowen, CI Lee, JL Burgess… - bioRxiv, 2017 - biorxiv.org
Abstract The Clinical Brain Disorders Branch of the Intramural Research Program at the
National Institutes of Health assembled a large collection of frozen post-mortem human …
National Institutes of Health assembled a large collection of frozen post-mortem human …