Transcription factor C/EBP homologous protein in health and diseases
Y Yang, L Liu, I Naik, Z Braunstein, J Zhong… - Frontiers in …, 2017 - frontiersin.org
C/EBP homologous protein (CHOP), known also as DNA damage-inducible transcript 3 and
as growth arrest and DNA damage-inducible protein 153 (GADD153), is induced in …
as growth arrest and DNA damage-inducible protein 153 (GADD153), is induced in …
Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins
Recent functional, proteomic and ribosome profiling studies in eukaryotes have concurrently
demonstrated the translation of alternative open-reading frames (altORFs) in addition to …
demonstrated the translation of alternative open-reading frames (altORFs) in addition to …
ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death
Disruption of protein folding in the endoplasmic reticulum (ER) causes ER stress. Activation
of the unfolded protein response (UPR) acts to restore protein homeostasis or, if ER stress is …
of the unfolded protein response (UPR) acts to restore protein homeostasis or, if ER stress is …
CHOP negatively regulates Polo-like kinase 2 expression via recruiting C/EBPα to the upstream-promoter in human osteosarcoma cell line during ER stress
T Shen, Y Li, Z Chen, S Liang, Z Guo, P Wang… - The international journal …, 2017 - Elsevier
Abstract Polo-like kinase 2 (Plk2) is a member of the serine/threonine protein kinase family
involved in cell-cycle regulation and cellular response to stresses. However, the alteration of …
involved in cell-cycle regulation and cellular response to stresses. However, the alteration of …
Endoplasmic reticulum stress regulates proliferation, migration and invasion of human ovarian cancer SKOV3 cells through PI3K/AKT/mTOR signaling pathway
N Yang, YJ Qu, Y Cheng, T Liang… - Cancer …, 2017 - content.iospress.com
OBJECTIVE: The study is to explore the role of tunicamycin-induced endoplasmic reticulum
stress (ERS) in human ovarian cancer (OC) SKOV3 cells proliferation, migration and …
stress (ERS) in human ovarian cancer (OC) SKOV3 cells proliferation, migration and …
Role of endoplasmic reticulum stress in silica-induced apoptosis in RAW264. 7 cells
YB Hu, WU Xia, XF Qin, W Lei, PH Pan - Biomedical and environmental …, 2017 - Elsevier
Objective We investigated the role of endoplasmic reticulum stress (ERS) in silica-induced
apoptosis in alveolar macrophages in vitro. Methods RAW264. 7 cells were incubated with …
apoptosis in alveolar macrophages in vitro. Methods RAW264. 7 cells were incubated with …
Polyurethane–polylactide-based material doped with resveratrol decreases senescence and oxidative stress of adipose-derived mesenchymal stromal stem cell …
K Kornicka, D Nawrocka, A Lis-Bartos, M Marędziak… - RSC …, 2017 - pubs.rsc.org
The aim of this study was to evaluate the influence of resveratrol (RES)-doped polyurethane
(TPU)–polylactide (PLA) biomaterials on the senescence and oxidative stress factor of …
(TPU)–polylactide (PLA) biomaterials on the senescence and oxidative stress factor of …
C/EBPβ LIP augments cell death by inducing osteoglycin
R Wassermann-Dozorets, M Rubinstein - Cell Death & Disease, 2017 - nature.com
Many types of tumor cell are devoid of the extracellular matrix proteoglycan osteoglycin
(Ogn), but its role in tumor biology is poorly studied. Here we show that RNAi of Ogn …
(Ogn), but its role in tumor biology is poorly studied. Here we show that RNAi of Ogn …
[HTML][HTML] Endoplasmic reticulum, oxidative stress and their complex crosstalk in neurodegeneration: proteostasis, signaling pathways and molecular chaperones
G Ambrosi, P Milani - AIMS Molecular Science, 2017 - aimspress.com
Cellular stress caused by protein misfolding, aggregation and redox imbalance is typical of
neurodegenerative disorders such as Parkinson's disease (PD) and Amyotrophic Lateral …
neurodegenerative disorders such as Parkinson's disease (PD) and Amyotrophic Lateral …
Compositions and methods for reducing C/EBP homologous protein activity in myeloid-derived suppressor cells
PC Rodriguez, AC Ochoa - US Patent 9,752,145, 2017 - Google Patents
US9752145B2 - Compositions and methods for reducing C/EBP homologous protein
activity in myeloid-derived suppressor cells - Google Patents US9752145B2 - Compositions …
activity in myeloid-derived suppressor cells - Google Patents US9752145B2 - Compositions …