After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

In the last decade, we witnessed discoveries that established Zn2+ as a second major
signalling metal ion in the transmission of information within cells and in communication …

Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …

In the last decade, iron and magnesium, both pure and alloyed, have been extensively
studied as potential biodegradable metals for medical applications. However, broad …

Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …

The efficacy of β-lactam antibiotics is threatened by the emergence and global spread of
metallo-β-lactamase (MBL) mediated resistance, specifically New Delhi metallo-β-lactamase …

The Rad50 hook interface is crucial for assembly and various functions of the Mre11
complex. Previous analyses suggested that Rad50 molecules interact within (intracomplex) …

Zincon (ZI) is one of the most common chromophoric chelating probes for the determination
of Zn 2+ and Cu 2+ ions. It is also known to bind other metal ions. However, literature data …

Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to
specific metals, but metal binding is not specific in vitro. Here we show that tight regulation of …

Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of
dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction …