The microenvironment plays a crucial role in the behavior of stem and progenitor cells. In the
heart, cardiac progenitor cells (CPCs) reside in specific niches, characterized by key …

Although exosomes were previously recognized as a mechanism for discharging useless
cellular components, growing evidence has elucidated their roles in conveying information …

Ischemic heart disease resulting from myocardial infarction (MI) is the most prevalent form of
heart disease in the United States. Post-MI cardiac remodeling is a multifaceted process that …

Abstract Background Mesenchymal stem cells (MSCs) have limited potential of cardiogenic
differentiation. In this study, we investigated the influence of long noncoding RNA …

The epicardium promotes neovascularization and cardiomyocyte regeneration by
generating vascular smooth muscle cells (SMCs) and producing regenerative factors after …

Neovascularization of the ischemic myocardium postinfarction is necessary to restore blood
flow to vulnerable cardiomyocytes and will be indispensable for prospective regenerative …

В обзоре обобщены данные литературы о развитии, строении, функции телоцитов
(Тц), их роли в сердце в норме и при патологии. В настоящее время Тц обнаружены во …

Aims: TCF21 knockout mice display cardiac defects, including ventricular septal defects
(VSDs). Functional rs12190287 polymorphisms located within the 3′ untranslated region …

Abstract Background: Angiotensin II (Ang II), the primary effector hormone of the renin-
angiotensin system (RAS), acts systemically or locally, being produced by the action of …

BACKGROUND: Unlike adult mammals, zebrafish can regenerate their heart. Several
mechanisms are essential to achieve regeneration; these include:• the de-differentiation and …