The bar is high to improve on current combination antiretroviral therapy (ART), now highly
effective, safe, and simple. However, antibodies that bind the HIV envelope are able to …

Detailed analysis of memory B-cell repertoires and evaluating the effector functions of
isolated monoclonal antibodies expands what we can learn from human vaccine trails, and …

The development of an effective vaccine against HIV-1 has proven to be challenging.
Broadly neutralizing antibodies (bNAbs), whilst exhibiting neutralization breadth and …

ABSTRACT A significant number of infants acquire HIV-1 through their infected mother's
breast milk, primarily due to limited access to antiretrovirals. Passive immunization with …

Human immunodeficiency virus (HIV) type 1 uses the CD4 molecule as its principal receptor
to infect T cells. HIV-1 integrates its viral genome into the host cell, leading to persistent …

Background: There is now intense interest in the role of HIV-specific antibodies and the
engagement of FcγR functions in the control and prevention of HIV infection. The analyses of …

As the HIV/AIDS pandemic still progresses, understanding the mechanisms governing viral
transmission as well as protection from HIV acquisition is fundamental. In this context …

HIV-1 superinfection, in which an infected individual acquires a second HIV-1 infection from
a different partner, is one of the only settings in which HIV acquisition occurs in the context of …

A complete picture of HIV antigenicity during early replication is needed to elucidate the full
range of options for controlling infection. Such information is frequently gained through …

Despite the wide availability of antiretroviral therapy (ART) prophylaxis during pregnancy,>
150,000 infants become infected through mother-to-child transmission (MTCT) of HIV …