Background Pain after surgery is not uncommon with 30% of patients reporting moderate to
severe postoperative pain. Early identification of patients prone to postoperative pain may …

Background Research suggests that peripheral and central nervous system sensitization
can contribute to the overall pain experience in peripheral musculoskeletal (MSK) …

Background Increased pain sensitivity is a putative risk factor for chronic pain and
consequently for analgesic use. Conversely, analgesic use may be a cause of increased …

Background Opioids are often used for pain treatment, but the response is often insufficient
and dependent on eg the pain condition, genetic factors and drug class. Thus, there is an …

Transcutaneous vagal nerve stimulation (TVNS) is a promising complementary method of
pain relief. However, the neural networks associated with its analgesic effects are still to be …

Objectives: Individuals with chronic pain often report increased pain sensitivity compared
with pain-free individuals; hence, it is crucial to determine whether and how different pain …

Background Chronic postherniorrhaphy inguinal pain (CPIP) is a complex, major health
problem. In the absence of recurrence or meshoma, laparoscopic retroperitoneal triple …

Opioids are increasingly used for treatment of chronic pain. However, they are only effective
in a subset of patients and have multiple side effects. Thus, studies using biomarkers for …

Background Refining and individualizing treatment of acute pain in the emergency
department (ED) is a high priority, given that painful complaints are the most common …