The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

Interleukin‐17 (IL‐17) induces the production of granulocyte colony‐stimulating factor (G‐
CSF) and chemokines such as CXCL1 and CXCL2 and is a cytokine that acts as an …

Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this
cytokine is a central player in immunity at the sites most exposed to microorganisms …

Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

There are many causes of inflammatory osteolysis, but regardless of etiology and cellular
contexts, the osteoclast is the bone-degrading cell. Thus, the impact of inflammatory …

Abstract Purpose of Review In the process of bone fracture healing, inflammation is thought
to be an essential process that precedes bone formation and remodeling. We review recent …

Osteoporosis, characterized by low bone mass and micro-architectural deterioration of bone
tissue with increased risk of fracture, can be categorized into two forms: primary and …

Postmenopausal osteoporosis (PMO) is a prevalent metabolic bone disease characterized
by bone loss and structural destruction, which increases the risk of fracture in …

Perturbations of the intestinal microbiome have been observed in patients with new-onset
and chronic autoimmune inflammatory arthritis. However, it is currently unknown whether …

The mechanisms that control physiological and pathological bone mass and turnover have
been extensively investigated over the past several decades. One surprising discovery that …