TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis
Signaling by the transforming growth factor–β (TGF-β) receptors I and II (TβRI/II) and the
primary cilia-localized sonic hedgehog (Shh) pathway promote cell migration and …
primary cilia-localized sonic hedgehog (Shh) pathway promote cell migration and …
The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways
M Sawai, Y Uchida, Y Ohno, M Miyamoto… - Journal of Biological …, 2017 - ASBMB
Differences among fatty acids (FAs) in chain length and number of double bonds create lipid
diversity. FA elongation proceeds via a four-step reaction cycle, in which the 3-hydroxyacyl …
diversity. FA elongation proceeds via a four-step reaction cycle, in which the 3-hydroxyacyl …
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals [S]
J Von Gerichten, K Schlosser, D Lamprecht… - Journal of lipid …, 2017 - ASBMB
Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-
galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in …
galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in …
Sphingosine metabolism as a therapeutic target in cutaneous melanoma
M Dany - Translational Research, 2017 - Elsevier
Melanoma is by far the most aggressive type of skin cancer with a poor prognosis in its
advanced stages. Understanding the mechanisms involved in melanoma pathogenesis …
advanced stages. Understanding the mechanisms involved in melanoma pathogenesis …
Sphingomyelins and ceramides with VLCPUFAs are excluded from low-density raft-like domains in differentiating spermatogenic cells
FXS Valtierra, MV Mateos, MI Aveldaño… - Journal of Lipid …, 2017 - ASBMB
Rat spermatogenic cells contain sphingomyelins (SMs) and ceramides (Cers) with very long-
chain PUFAs (VLCPUFAs) in nonhydroxylated (nV) and 2-hydroxylated (hV) forms. How …
chain PUFAs (VLCPUFAs) in nonhydroxylated (nV) and 2-hydroxylated (hV) forms. How …
[PDF][PDF] The role of ceramide synthase 2 in sphingosine-1-phosphate-mediated thymic egress
M Rieck - 2017 - core.ac.uk
The generation of bone marrow chimeras, as well as the transplantation of thymic lobes
under the kidney capsule of recipient mice (see 4.2. 1 and 4.2. 2) were performed in …
under the kidney capsule of recipient mice (see 4.2. 1 and 4.2. 2) were performed in …
Sphingomyelins and ceramides with very-long-chain PUFA are excluded from lowdensity, raft-like domains in differentiating spermatogenic cells
FX Santiago Valtierra, MV Mateos, MI Aveldaño… - 2017 - notablesdelaciencia.conicet.gov.ar
Rat spermatogenic cells contain sphingomyelins (SM) and ceramides (Cer) with very long
chain (VLC) PUFA, in nonhydroxylated (nV) and 2-hydroxylated (hV) forms. How these …
chain (VLC) PUFA, in nonhydroxylated (nV) and 2-hydroxylated (hV) forms. How these …
[PDF][PDF] Megumi Sawai, Yukiko Uchida, Yusuke Ohno, Masatoshi Miyamoto, Chieko Nishioka
S Itohara, T Sassa, A Kihara - 2017 - researchgate.net
1Both authors contributed equally to this work. 2To whom correspondence should be
addressed: Akio Kihara, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 …
addressed: Akio Kihara, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 …